Rodrigues M, Hidayat A, Karesh J
Department of Ophthalmology, University of Maryland, School of Medicine, Baltimore.
Am J Ophthalmol. 1988 Nov 15;106(5):595-600. doi: 10.1016/0002-9394(88)90593-4.
A 72-year-old woman had epibulbar nodules and a blind eye following trauma in childhood. Histologic examination disclosed a pleomorphic adenocarcinoma of ciliary epithelium with invasion of the epibulbar region, retina, retinal pigment epithelium, and optic nerve. The diagnosis was confirmed by histochemical stains and electron microscopy. The pigmented and nonpigmented neoplastic cells of the ciliary epithelium had a patchy basement membrane around the cell membrane and produced hyaluronic acid in the stroma.
一名72岁女性在童年时期遭受创伤后出现眼球表面结节和失明。组织学检查显示为睫状体上皮多形性腺癌，侵犯眼球表面区域、视网膜、视网膜色素上皮和视神经。组织化学染色和电子显微镜检查证实了诊断。睫状体上皮的色素性和非色素性肿瘤细胞在细胞膜周围有不连续的基底膜，并在基质中产生透明质酸。
