De Soyza K, Garland D G
Metropolitan Police Forensic Science Laboratory, London, U.K.
Forensic Sci Int. 1988 Jul-Aug;38(1-2):129-37. doi: 10.1016/0379-0738(88)90016-3.
Leb positive individuals may phenotypically express both Lea and Leb in their secreted body fluids. Therefore, the interpretation of a Le(a + ,b-), non-secretor result is dependent on the absence of Leb. This study emphasises the importance of accurate procedure and biased selection of antisera such that Leb is preferentially detected in comparison with Lea. The relationship of the ABO group to the expression of Le is discussed in conjunction with the selection of samples for testing antisera and inclusion as control standards.
Leb阳性个体在其分泌的体液中可能在表型上同时表达Lea和Leb。因此,Le(a + ,b-)、非分泌型结果的解释取决于Leb的缺失。本研究强调了准确的操作程序和有偏向性地选择抗血清的重要性,以便与Lea相比能优先检测到Leb。在选择用于检测抗血清的样本以及纳入作为对照标准时,讨论了ABO血型组与Le表达的关系。