Psaltis Alkis J, Li Gang, Vaezeafshar Reza, Cho Kyu-Sup, Hwang Peter H
Department of Otolaryngology-Head and Neck Surgery, University of Adelaide, Adelaide, South Australia, Australia.
Laryngoscope. 2014 Oct;124(10):2216-23. doi: 10.1002/lary.24654. Epub 2014 Apr 2.
OBJECTIVES/HYPOTHESIS: To compare three existing endoscopic scoring systems and a newly proposed modified scoring system for the assessment of patients with chronic rhinosinusitis (CRS).
Blinded, prospective cohort study.
CRS patients completed two patient-reported outcome measures (PROMs)-the visual analogue scale (VAS) symptom score and the Sino-Nasal Outcome Test-22 (SNOT-22)-and then underwent a standardized, recorded sinonasal endoscopy. Videos were scored by three blinded rhinologists using three scoring systems: the Lund-Kennedy (LK) endoscopic score; the Discharge, Inflammation, Polyp (DIP) score; and the Perioperative Sinonasal Endoscopic score. The videos were further scored using a modified Lund-Kennedy (MLK) endoscopic scoring system, which retains the LK subscores of polyps, edema, and discharge but eliminates the scoring of scarring and crusting. The systems were compared for test-retest and inter-rater reliability as well as for their correlation with PROMs.
One hundred two CRS patients were enrolled. The MLK system showed the highest inter-rater and test-retest reliability of all scoring systems. All systems except for the DIP correlated with total VAS scores. The MLK was the only system that correlated with the symptom subscore of the SNOT-22 in both unoperated and postoperative patients.
Modification of the LK system by excluding the subscores of scarring and crusting improves its reliability and its correlation with PROMs. In addition, the MLK system retains the familiarity of the widely used LK system and is applicable to any patient irrespective of surgical status. The MLK system may be a more suitable and reliable endoscopic scoring system for clinical practice and outcomes research.
目的/假设:比较三种现有的内镜评分系统和一种新提出的改良评分系统,用于评估慢性鼻-鼻窦炎(CRS)患者。
盲法前瞻性队列研究。
CRS患者完成两项患者报告结局指标(PROMs)——视觉模拟量表(VAS)症状评分和鼻鼻窦结局测试-22(SNOT-22),然后接受标准化的、有记录的鼻鼻窦内镜检查。由三位盲法鼻科医生使用三种评分系统对视频进行评分:伦德-肯尼迪(LK)内镜评分;分泌物、炎症、息肉(DIP)评分;以及围手术期鼻鼻窦内镜评分。使用改良的伦德-肯尼迪(MLK)内镜评分系统对视频进一步评分,该系统保留了LK系统中息肉、水肿和分泌物的子评分,但取消了瘢痕形成和结痂的评分。比较各系统的重测信度和评分者间信度,以及它们与PROMs的相关性。
纳入102例CRS患者。MLK系统在所有评分系统中显示出最高的评分者间信度和重测信度。除DIP外,所有系统均与VAS总分相关。MLK是唯一在未手术和术后患者中均与SNOT-22症状子评分相关的系统。
通过排除瘢痕形成和结痂的子评分对LK系统进行改良,提高了其信度及其与PROMs的相关性。此外,MLK系统保留了广泛使用的LK系统的易用性,适用于任何患者,无论其手术状态如何。MLK系统可能是临床实践和结局研究中更合适、更可靠的内镜评分系统。