WPI-Advanced Institute for Materials Research, Tohoku University, Sendai, 980-8578, Japan.
Adv Mater. 2014 May 28;26(20):3290-6. doi: 10.1002/adma.201305804. Epub 2014 Mar 11.
A "sticker-like" PLGA nanosheet with microgrooved patterns is developed through a facile combination of spin coating and micropatterning techniques. The resulting microgrooved PLGA nanosheets can be physically adhered on flat or porous surfaces with excellent stability in aqueous environments and can harness the spatial arrangements of cells, which make it a promising candidate for generating biomimic periosteum for bone regenerative applications.
一种“贴纸样”的聚乳酸-乙醇酸共聚物纳米片，具有微槽图案，是通过旋涂和微图案化技术的简单组合开发的。所得的微槽聚乳酸-乙醇酸共聚物纳米片可以物理地附着在平面或多孔表面上，在水环境中具有优异的稳定性，并可以利用细胞的空间排列，使其成为用于骨再生应用的仿生骨膜的有前途的候选物。
