Wang Li, Cai Sheng-Chao, Qin Xiao-Feng, Yuan Wei-Hua, He Cheng-Gong, Cao Yun-Yan
Zhongguo Zhen Jiu. 2013 Dec;33(12):1081-4.
To observe clinical curative effect of cake-separated moxibustion on impaired glucose regulation (IGR) and explore its action mechanism.
Sixty cases were randomly divided into a simple lifestyle intervention group (control group) and a cake-separated moxibustion combined with lifestyle intervention group (observation group), 30 cases in each one. The control group was treated with lifestyle intervention. Based on lifestyle intervention, cake-separated moxibustion at Pishu (BL 20), Weishu (BL 21) and Yishu (EX-B 3) was applied to the observation group. Fast plasma glucose (FPG), two hours plasma glucose after oral glucose tolerance test (OGTT2hPG), fasting insulin (FINS), homa insulin resistance index (HOMA-IR), blood lipid, body mass index (BMI) and waist circumference (WC) were observed in the two groups before and after treatment.
After treatment, the OGTT2hPG and FPG were both decreased significantly (both P<0.05) in the two groups, compared between the two groups, the differences of FPG [(0.41 +/- 0.42) mmol/L vs (0.05 +/- 0.08)mmol/L] and OGTT2hPG [(0.85 +/- 0.53)mmol/L vs (0.17 +/- 0.19)mmol/L] were both statistically significant. There were no significant changes in FINS, HOMA-IR, blood lipid, BMI and WC in the control group before and after treatment (all P>0.05), but FINS, HOMA-IR levels, triglycerides (TG), total cholest-erol (TC), low density lipoprotein (LDL-C), BMI and WC in the observation group were decreased obviously after treatment (all P<0.05), which had statistical differences between the two groups (all P<0.05).
The cake-separated moxibustion combined with lifestyle intervention can obviously control blood glucose levels, improve insulin resistance and blood lipid levels, decrease BMI and WC.
观察隔饼灸对糖调节受损（IGR）的临床疗效并探讨其作用机制。
将60例患者随机分为单纯生活方式干预组（对照组）和隔饼灸联合生活方式干预组（观察组），每组30例。对照组采用生活方式干预。观察组在生活方式干预基础上，采用隔饼灸脾俞（BL 20）、胃俞（BL 21）和胰俞（EX - B 3）。观察两组治疗前后的空腹血糖（FPG）、口服葡萄糖耐量试验后2小时血糖（OGTT2hPG）、空腹胰岛素（FINS）、稳态模型胰岛素抵抗指数（HOMA - IR）、血脂、体重指数（BMI）和腰围（WC）。
治疗后，两组的OGTT2hPG和FPG均显著降低（均P<0.05），两组比较，FPG[（0.41±0.42）mmol/L对（0.05±0.08）mmol/L]和OGTT2hPG[（0.85±0.53）mmol/L对（0.17±0.19）mmol/L]差异均有统计学意义。对照组治疗前后FINS、HOMA - IR、血脂、BMI和WC无明显变化（均P>0.05），但观察组治疗后FINS、HOMA - IR水平、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白（LDL - C）、BMI和WC明显降低（均P<0.05），两组间比较差异均有统计学意义（均P<0.05）。
隔饼灸联合生活方式干预能明显控制血糖水平，改善胰岛素抵抗和血脂水平，降低BMI和WC。
