Chang Shiow-Ru, Chen Kuang-Ho, Lin Ming-I, Lin Ho-Hsiung, Huang Lian-Hua, Lin Wei-An
School of Nursing, College of Medicine and Hospital, National Taiwan University, Taipei, Taiwan.
J Adv Nurs. 2014 Oct;70(10):2245-56. doi: 10.1111/jan.12374. Epub 2014 Mar 12.
To examine changes in health-related quality of life throughout the course of pregnancy and among three pairs of consecutive periods (pre-pregnancy to early pregnancy, early to middle pregnancy and middle to late pregnancy), as well as to identify associated obstetric factors during the entire period of pregnancy.
Only sparse data are available concerning the profiles of health-related quality of life throughout pregnancy.
A within-subject comparison was undertaken.
In total, 358 women completed the Taiwanese version of the Medical Outcomes Study Short Form-36 Health Questionnaire and a demographic-obstetric questionnaire at three stages of pregnancy at a medical centre. The participants were recruited between 2009-2010. A generalized estimating equation regression model was employed for the repeated measures.
The scores for physical component summary decreased significantly throughout early, middle and late pregnancy. The scores for mental component summary increased. The scores for physical, mental component summary and the eight domains of health-related quality of life decreased significantly from pre-pregnancy to early pregnancy. After adjusting for demographic and clinical factors, significant factors predicting physical component summary during pregnancy included stage of pregnancy and previous infertility. The factors predicting mental component summary included stage of pregnancy, parity and medical condition.
The results revealed the dynamic pattern of perceived health status by the Taiwanese pregnant women in their surrounding socio-cultural context and identified the stage of pregnancy and obstetric factors predicting health-related quality of life.
研究孕期全过程以及三个连续阶段（孕前至孕早期、孕早期至孕中期、孕中期至孕晚期）与健康相关的生活质量变化，并确定整个孕期相关的产科因素。
关于孕期与健康相关的生活质量概况的数据稀少。
进行了一项受试者内比较。
共有358名女性在一家医疗中心孕期的三个阶段完成了台湾版医学结局研究简表36健康调查问卷以及一份人口统计学 - 产科调查问卷。参与者于2009年至2010年招募。采用广义估计方程回归模型进行重复测量。
在孕早期、孕中期和孕晚期，身体成分总结得分显著下降。心理成分总结得分上升。从孕前到孕早期，身体、心理成分总结以及与健康相关的生活质量的八个领域得分显著下降。在调整人口统计学和临床因素后，孕期预测身体成分总结的显著因素包括孕期阶段和既往不孕史。预测心理成分总结的因素包括孕期阶段、产次和健康状况。
结果揭示了台湾孕妇在其周围社会文化背景下感知健康状况的动态模式，并确定了孕期阶段和预测与健康相关生活质量的产科因素。
