Cojocaru M, Chicoş B
Rom J Intern Med. 2013 Jul-Dec;51(3-4):131-4.
Recently, reports have suggested grouping different autoimmune conditions that are triggered by external stimuli as a single syndrome called autoimmune syndrome induced by adjuvants (ASIA). This syndrome is characterized by the appearance of myalgia, myositis, muscle weakness, arthralgia, arthritis, chronic fatigue, sleep disturbances, cognitive impairment and memory loss, and the possible emergence of a demyelinating autoimmune disease caused by systemic exposure after vaccines and adjuvants. As there are no markers for ASIA, the authors intend to present ASIA, or Shoenfeld's syndrome, as an autoimmune syndrome induced by adjuvants.
最近,有报告建议将由外部刺激引发的不同自身免疫性疾病归为一种单一综合征,称为佐剂诱导的自身免疫综合征(ASIA)。该综合征的特征表现为肌痛、肌炎、肌肉无力、关节痛、关节炎、慢性疲劳、睡眠障碍、认知障碍和记忆力减退,以及在接种疫苗和使用佐剂后因全身暴露可能出现的脱髓鞘自身免疫性疾病。由于ASIA没有标志物,作者打算将ASIA或肖费尔德综合征作为佐剂诱导的自身免疫综合征来介绍。