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针对青少年特发性脊柱侧弯的医学治疗方法的实际证据。

Actual evidence in the medical approach to adolescents with idiopathic scoliosis.

作者信息

Negrini S, De Mauroy J C, Grivas T B, Knott P, Kotwicki T, Maruyama T, O'Brien J P, Rigo M, Zaina F

机构信息

Physical and Rehabilitation Medicine Department of Clinical and Experimental Sciences University of Brescia, Brescia, Italy -

出版信息

Eur J Phys Rehabil Med. 2014 Feb;50(1):87-92.

Abstract

Idiopathic scoliosis (IS) is a three-dimensional deformity of the spine and trunk. The most common form involve adolescents. The prevalence is 2-3% of the population, with 1 out of 6 patients requiring treatment of which 25% progress to surgery. Physical and rehabilitation medicine (PRM) plays a primary role in the so-called conservative treatment of adolescents with IS, since all the therapeutic tools used (exercises and braces) fall into the PRM domain. According to a Cochrane systematic review there is evidence in favor of bracing, even if it is of low quality. Recently, a controlled prospective trial including a randomised arm gave more strength to this conclusion. Another Cochrane review shows that there is evidence in favor of exercises as an adjunctive treatment, but of low quality. Three meta-analysis have been published on bracing: one shows that bracing does not reduce surgery rates, but studies with bracing plus exercises were not included and had the highest effectiveness; another shows that full time is better than part-time bracing; the last focuses on observational studies following the Scoliosis Research Society (SRS) criteria and shows that not all full time rigid bracing are the same: some have the highest effectiveness, others have less than elastic and nighttime bracing. Two very important RCTs failed in recruitment, showing that in the field of bracing for scoliosis RCTs are not accepted by the patients. Consensuses by the international Society on Scoliosis Orthopedic and Rehabilitation Treatment (SOSORT) show that there is no agreement among experts either on the best braces or on their biomechanical action, and that compliance is a matter of clinical more than patients' behavior (there is strong agreement on the management criteria to achieve best results with bracing). A systematic review of all the existing studies shows effectiveness of exercises, and that auto-correction is their main goal. A systematic review shows that there are no studies on manual treatment. The SOSORT Guidelines offer the actual standard of conservative care.

摘要

特发性脊柱侧凸(IS)是脊柱和躯干的三维畸形。最常见的形式发生在青少年中。患病率为人口的2%-3%,每6名患者中有1名需要治疗,其中25%会进展到手术治疗。物理与康复医学(PRM)在青少年IS的所谓保守治疗中起主要作用,因为所有使用的治疗工具(运动和支具)都属于PRM领域。根据一项Cochrane系统评价,有证据支持使用支具,即使证据质量较低。最近,一项包括随机分组的对照前瞻性试验进一步支持了这一结论。另一项Cochrane综述表明,有证据支持将运动作为辅助治疗,但证据质量较低。关于支具已经发表了三项荟萃分析:一项表明支具不能降低手术率,但未纳入支具加运动的研究,而这些研究的有效性最高;另一项表明全天佩戴支具优于部分时间佩戴;最后一项关注遵循脊柱侧凸研究学会(SRS)标准的观察性研究,表明并非所有全天刚性支具都是相同的:有些支具有效性最高,而另一些支具的有效性低于弹性支具和夜间支具。两项非常重要的随机对照试验(RCT)在招募患者方面失败了,这表明在脊柱侧凸支具治疗领域,RCT不被患者接受。国际脊柱侧凸矫形与康复治疗协会(SOSORT)的共识表明,专家们在最佳支具及其生物力学作用方面没有达成一致,而且依从性更多是临床问题而非患者行为问题(在实现支具最佳效果的管理标准方面存在强烈共识)。对所有现有研究的系统评价表明运动具有有效性,且自我矫正为其主要目标。一项系统评价表明没有关于手法治疗的研究。SOSORT指南提供了保守治疗的实际标准。

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