Lim C S, Abrams P
Bristol Urological Institute, Southmead Hospital, UK.
World J Urol. 1995;13(1):34-9. doi: 10.1007/BF00182664.
The treatment of benign prostatic hyperplasia and the definition of bladder-outlet obstruction has preoccupied urologists and researchers in recent years. Bladder-outlet obstruction can be defined only by pressure-flow measurement. Various methods of analysis of pressure-flow data have been proposed. The Abrams-Griffiths nomogram is an easy method of classifying these data to distinguish between the presence or absence of obstruction. Using the values for the maximal flow and the corresponding voiding detrusor pressure a point can be plotted on the nomogram that determines whether the bladder outlet is obstructed, unobstructed, or equivocally obstructed. For those that fall in the equivocal zone, further criteria for the mean slope of the pressure-flow plot and the minimal voiding detrusor pressure are used to determine whether there is obstruction or not. The nomogram's prognostic value in predicting the outcome of prostatectomy has been studied and found to be excellent. The Abrams-Griffiths nomogram can be modified by assigning an Abrams-Griffiths number to each set of pressure-flow data. This number is easy to calculate and use and gives a continuous variable that can be used to evaluate the effects of therapy. Although the Abrams-Griffiths nomogram and number are somewhat simplistic, none of the more complex methods of pressure-flow analysis have been shown to be better predictors of treatment outcome to date.
近年来，良性前列腺增生的治疗以及膀胱出口梗阻的定义一直困扰着泌尿外科医生和研究人员。膀胱出口梗阻只能通过压力-流率测定来定义。人们提出了各种分析压力-流率数据的方法。艾布拉姆斯-格里菲思列线图是一种对这些数据进行分类以区分是否存在梗阻的简便方法。利用最大尿流率值和相应的排尿期逼尿肌压力值，可以在列线图上绘制一个点，该点可确定膀胱出口是梗阻、通畅还是可疑梗阻。对于落在可疑区域的情况，可使用压力-流率曲线的平均斜率和最小排尿期逼尿肌压力的进一步标准来确定是否存在梗阻。该列线图在预测前列腺切除术结果方面的预后价值已得到研究，结果显示非常出色。通过为每组压力-流率数据赋予一个艾布拉姆斯-格里菲思数值，可以对艾布拉姆斯-格里菲思列线图进行修正。这个数值易于计算和使用，并且提供了一个可用于评估治疗效果的连续变量。尽管艾布拉姆斯-格里菲思列线图和数值有些过于简单，但迄今为止，没有一种更复杂的压力-流率分析方法被证明是更好的治疗结果预测指标。
