Bock K, Heywang-Köbrunner S, Regitz-Jedermann L, Hecht G, Kääb-Sanyal V
Referenzzentrum Mammographie Südwest/Marburg, Bahnhofstr. 7, 35037, Marburg, Deutschland,
Radiologe. 2014 Mar;54(3):205-10. doi: 10.1007/s00117-013-2581-7.
The concept of mammography screening is based on the expectation that early diagnosis in a preclinical tumor stage enables less invasive treatment with a better prognosis than detection in advanced tumor stages. Mammography screening was implemented in European countries after results from large randomized controlled trials showed that regular screening led to a significant reduction in breast cancer mortality by 25-30 %. Recently, a major review of breast cancer screening services in Europe concluded that the benefits of screening clearly outweighed the disadvantages. In comparison to other European screening nations the German mammography screening program is relatively new. The challenge to prove the effectiveness by reduction in mortality still has to be solved. Continuous evaluation and optimization concerning the quality of structure, processes and results already confirm the high quality of the nationwide German screening services.
乳腺钼靶筛查的概念基于这样一种期望,即在临床前肿瘤阶段进行早期诊断,与在肿瘤晚期进行检测相比,能够采用侵入性较小的治疗方法,且预后更好。在大型随机对照试验结果表明定期筛查可使乳腺癌死亡率显著降低25%-30%之后,欧洲国家实施了乳腺钼靶筛查。最近,对欧洲乳腺癌筛查服务的一项主要综述得出结论,筛查的益处明显大于弊端。与其他欧洲筛查国家相比,德国的乳腺钼靶筛查计划相对较新。通过降低死亡率来证明其有效性这一挑战仍有待解决。对结构、流程和结果质量的持续评估和优化已经证实了德国全国筛查服务的高质量。