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[老年人药物依从性低的相关因素]

[Factors associated with low adherence to medication in older adults].

作者信息

Tavares Noemia Urruth Leão, Bertoldi Andréa Dâmaso, Thumé Elaine, Facchini Luiz Augusto, França Giovanny Vinícius Araújo de, Mengue Sotero Serrate

出版信息

Rev Saude Publica. 2013 Dec;47(6):1092-101. doi: 10.1590/s0034-8910.2013047004834.

DOI:10.1590/s0034-8910.2013047004834
PMID:24626547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4206106/
Abstract

OBJECTIVE

To assess factors associated with low adherence to pharmacotherapy in older adults.

METHODS

Cross-sectional population-based study, with a representative sample of 1,593 individuals aged 60 or older, living in the urban area of Bagé, RS, Southern Brazil, in 2008. A multiple stage sampling model was used. The data were collected through individual household interviews. The analyses of the association between low adherence regarding pharmacotherapy, measured using the Brief Medication Questionnaire (BMQ), and demographic, socioeconomic, behavioral, health, assistance and prescription factors were carried out applying Poisson regression model to assess crude and adjusted prevalence ratios, their respective 95% confidence intervals and p-value (Wald test).

RESULTS

Around 78.0% of individuals reported have taken at least one medication in the seven days prior to the interview. Of these, approximately one third (28.7%) were considered to have low adherence to the treatment. The factors significantly associated to low adherence to treatment were: age (65 to 74 years old), not having health insurance, having to purchase (totally or partially) their own medicines, having three or more morbidities, having functional disabilities and using three or more medicines.

CONCLUSIONS

The increased use of medicines by older adults, because of the high prevalence of non-communicable diseases in this group, and the access to the treatment need to be considered by health care professionals regarding fostering adherence to treatment, which increases therapeutic solutions and quality of life among older people.

摘要

目的

评估与老年人药物治疗依从性低相关的因素。

方法

基于人群的横断面研究,于2008年在巴西南部南里奥格兰德州巴热市城区选取了1593名60岁及以上的个体作为代表性样本。采用多阶段抽样模型。通过个人入户访谈收集数据。使用简明用药问卷(BMQ)衡量药物治疗依从性低的情况,并应用泊松回归模型分析其与人口统计学、社会经济、行为、健康、医疗救助及处方因素之间的关联,以评估粗患病率和调整患病率比值、各自的95%置信区间及p值( Wald检验)。

结果

约78.0%的个体报告在访谈前七天内至少服用过一种药物。其中,约三分之一(28.7%)被认为治疗依从性低。与治疗依从性低显著相关的因素有:年龄(65至74岁)、没有医疗保险、必须(全部或部分)自行购买药品、患有三种或更多种疾病、有功能障碍以及使用三种或更多种药物。

结论

由于该群体中非传染性疾病的高患病率,老年人用药量增加,医护人员在促进治疗依从性时需要考虑治疗的可及性,这会增加老年人的治疗方案并提高其生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1902/4206106/e1dfc90660e3/rsp-47-06-1092-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1902/4206106/e1dfc90660e3/rsp-47-06-1092-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1902/4206106/e1dfc90660e3/rsp-47-06-1092-g01.jpg

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本文引用的文献

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2
Risk factors for medication nonadherence in older adults with cognitive impairment who live alone.独居认知功能障碍老年患者药物治疗不依从的危险因素。
Int J Geriatr Psychiatry. 2012 Dec;27(12):1275-82. doi: 10.1002/gps.3778. Epub 2012 Feb 15.
3
The Brief Medication Questionnaire and Morisky-Green test to evaluate medication adherence.简短用药问卷和 Morisky-Green 测试评估用药依从性。
与心力衰竭患者药物治疗不依从相关的因素。
Rev Lat Am Enfermagem. 2024 Aug 30;32:e4302. doi: 10.1590/1518-8345.6756.4302. eCollection 2024.
4
Prediction of Multimorbidity in Brazil: Latest Fifth of a Century Population Study.巴西多病共存预测:最新五分之一世纪人口研究。
JMIR Public Health Surveill. 2023 May 30;9:e44647. doi: 10.2196/44647.
5
Difficulties in the use of medications by elderly people followed up in a cohort study in Southern Brazil.巴西南部一项队列研究中老年人用药困难情况。
Rev Bras Epidemiol. 2023 Mar 10;26:e230020. doi: 10.1590/1980-549720230020.2. eCollection 2023.
6
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Int J Environ Res Public Health. 2023 Jan 14;20(2):1537. doi: 10.3390/ijerph20021537.
7
Evaluating home injection compared with healthcare-setting injection of somatostatin analogs: a systematic literature review.评估家庭注射与在医疗保健环境中注射生长抑素类似物:系统文献回顾。
Endocrine. 2023 Mar;79(3):527-536. doi: 10.1007/s12020-022-03227-0. Epub 2022 Nov 11.
8
Health literacy and adherence to the pharmacological treatment by people with arterial hypertension.健康素养与动脉高血压患者对药物治疗的依从性。
Rev Bras Enferm. 2022 Aug 8;75(6):e20220008. doi: 10.1590/0034-7167-2022-0008. eCollection 2022.
9
Variables associated with adherence to the treatment of type 2 diabetes mellitus among elderly people.与老年人2型糖尿病治疗依从性相关的变量。
Diabetol Int. 2021 Jun 17;13(1):160-168. doi: 10.1007/s13340-021-00518-1. eCollection 2022 Jan.
10
Specific features of rational pharmacotherapy in elderly patients.老年患者合理药物治疗的特点。
Eur J Hosp Pharm. 2023 Nov;30(6):322-327. doi: 10.1136/ejhpharm-2021-002980. Epub 2021 Nov 18.
Rev Saude Publica. 2012 Apr;46(2):279-89. doi: 10.1590/s0034-89102012005000013. Epub 2012 Feb 14.
4
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Cad Saude Publica. 2011;27 Suppl 3:S427-34. doi: 10.1590/s0102-311x2011001500013.
6
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7
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Am J Public Health. 2011 May;101(5):868-74. doi: 10.2105/AJPH.2009.184648. Epub 2010 Aug 19.
10
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Med Clin North Am. 2009 May;93(3):753-69. doi: 10.1016/j.mcna.2009.02.007.