Furqan Muhammad, Chen Yamei, Akinleye Akintunde, Sarungbam Judy, Gass Alan, Seiter Karen, Liu Delong
Division of Hematology and Oncology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY, 10595, USA.
Front Med. 2014 Jun;8(2):254-8. doi: 10.1007/s11684-014-0319-1. Epub 2014 Mar 14.
Mantle cell lymphoma is an aggressive subtype of B cell non-Hodgkin lymphoma. It can progress to leukemic phase but frank leukemic picture at initial presentation is not common. Leukemic phase indicates advance stage of the disease and generally associated with extensive extra-nodal involvement. Pericardial invasion has been reported, however we could not find a report of myocardial infiltration by this disease since the appraisal of the term "mantle cell lymphoma" in 1992. Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which complicates the treatment decisions.
套细胞淋巴瘤是B细胞非霍奇金淋巴瘤的一种侵袭性亚型。它可进展至白血病期，但初诊时出现典型白血病表现并不常见。白血病期提示疾病处于晚期，通常与广泛的结外受累相关。心包侵犯已有报道，然而自1992年“套细胞淋巴瘤”这一术语被定义以来，我们尚未发现有该疾病心肌浸润的报道。在此，我们报告一例套细胞白血病累及心脏导致心源性休克的病例，这使治疗决策变得复杂。
