套细胞淋巴瘤的皮肤表现：一项全面的文献综述

Cutaneous manifestations of mantle cell lymphoma: an extensive literature review.

作者信息

Geropoulos Georgios, Psarras Kyriakos, Vlachaki Efthymia, Kakos Christos, Vetsiou Evangelia, Vamvakis Kyriakos, Sousos Nikolaos, Mpouras Vasileios, Symeonidis Nikolaos, Pavlidis Efstathios T, Pavlidis Theodoros E

机构信息

Second Propedeutical Department of Surgery, Aristotle University of Thessaloniki, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Greece.

Second Department of Internal Medicine, Aristotle University of Thessaloniki, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Greece.

出版信息

Acta Dermatovenerol Alp Pannonica Adriat. 2020 Dec;29(4):185-191.

PMID:33348938

Abstract

Mantle cell lymphomas account for about 2 to 10% of non-Hodgkin B-cell lymphomas. Despite the cellular maturity of B-cell lymphomas, the disease is aggressive in the majority of cases and its course is unpredictable. The clinical presentation is variable, and multiple nodal and extranodal manifestations have been described. Cutaneous infiltration is an uncommon (2-6%) location of the disease. An extensive review of the literature was performed, and 24 case reports and five case series were found describing cutaneous locations. These data were thoroughly studied in order to present their clinical and laboratory characteristics in this review.

摘要

套细胞淋巴瘤约占非霍奇金B细胞淋巴瘤的2%至10%。尽管B细胞淋巴瘤具有细胞成熟性，但在大多数情况下该疾病具有侵袭性，其病程不可预测。临床表现多样，已描述了多种淋巴结和结外表现。皮肤浸润是该疾病不常见（2% - 6%）的发病部位。我们对文献进行了广泛回顾，发现了24篇病例报告和5个病例系列描述了皮肤发病部位。为了在本综述中呈现其临床和实验室特征，对这些数据进行了深入研究。