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严重创伤出血管理的最新进展

Recent advances of hemorrhage management in severe trauma.

作者信息

El Sayad Mohamed, Noureddine Hussein

机构信息

Trauma and Orthopaedics, Wishaw General Hospital, Wishaw, UK.

Trauma and Orthopaedics, Ninewells Hospital, Dundee, UK.

出版信息

Emerg Med Int. 2014;2014:638956. doi: 10.1155/2014/638956. Epub 2014 Jan 30.

DOI:10.1155/2014/638956
PMID:24627809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3929186/
Abstract

Trauma is one of the most common causes of mortality worldwide with a substantial percentage of deaths resulting secondary to haemorrhages, which are preventable and treatable when adequately managed. This paper offers a review of the current literature on how to successfully resuscitate patients with major haemorrhage.

摘要

创伤是全球最常见的死亡原因之一，相当大比例的死亡是由出血继发导致的，而这些出血在得到妥善处理时是可预防和可治疗的。本文对当前有关如何成功复苏大出血患者的文献进行了综述。

相似文献

1
Recent advances of hemorrhage management in severe trauma.严重创伤出血管理的最新进展
Emerg Med Int. 2014;2014:638956. doi: 10.1155/2014/638956. Epub 2014 Jan 30.
2
Preventable deaths from hemorrhage at a level I Canadian trauma center.加拿大一级创伤中心因出血导致的可预防死亡情况。
J Trauma. 2007 Jan;62(1):142-6. doi: 10.1097/01.ta.0000251558.38388.47.
3
4
Preventable and potentially preventable deaths in severely injured patients: a retrospective analysis including patterns of errors.重伤患者中可预防和潜在可预防的死亡：一项包括错误模式的回顾性分析
Eur J Trauma Emerg Surg. 2017 Aug;43(4):481-489. doi: 10.1007/s00068-016-0670-9. Epub 2016 Apr 12.
5
Retinal haemorrhages in- head trauma resulting from falls: differential diagnosis with non-accidental trauma in patients younger than 2 years of age.跌倒导致头部外伤时的视网膜出血：2岁以下患者非意外性外伤的鉴别诊断
Childs Nerv Syst. 2008 Jul;24(7):815-20. doi: 10.1007/s00381-008-0583-y. Epub 2008 Feb 13.
6
Opportunities for improvement in the management of patients who die from haemorrhage after trauma.创伤后出血死亡患者管理中的改进机会。
Br J Surg. 2013 May;100(6):749-55. doi: 10.1002/bjs.9096. Epub 2013 Mar 11.
7
Minimizing preventable trauma deaths in a limited-resource setting: a test-case of a multidisciplinary panel review approach at the Komfo Anokye Teaching Hospital in Ghana.在资源有限的环境中尽量减少可预防的创伤死亡：加纳Komfo Anokye教学医院多学科小组审查方法的一个测试案例。
World J Surg. 2014 Jul;38(7):1707-12. doi: 10.1007/s00268-014-2452-z.
8
Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention.一级创伤中心的753例连续死亡病例：预防伤害的理由
J Trauma. 2003 Jan;54(1):66-70; discussion 70-1. doi: 10.1097/00005373-200301000-00009.
9
Trauma-related preventable deaths in Berlin 2010: need to change prehospital management strategies and trauma management education.2010 年柏林创伤相关可预防死亡：需要改变院前管理策略和创伤管理教育。
World J Surg. 2013 May;37(5):1154-61. doi: 10.1007/s00268-013-1964-2.
10
Transfusion strategies for major haemorrhage in trauma.创伤性大出血的输血策略。
Br J Haematol. 2019 Feb;184(4):508-523. doi: 10.1111/bjh.15737. Epub 2018 Dec 27.

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Highly Absorbent Ultrafast Self-Gelling Starch Microparticles for Robust Wet-Tissue Adhesion and Instant Hemostasis.用于强力湿组织粘附和即时止血的高吸水性超快自凝胶淀粉微粒
Adv Sci (Weinh). 2025 May;12(19):e2501857. doi: 10.1002/advs.202501857. Epub 2025 Mar 24.
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Sticky Science: Using Complex Coacervate Adhesives for Biomedical Applications.粘性科学：将复合凝聚层粘合剂用于生物医学应用
Adv Healthc Mater. 2025 Jan;14(2):e2402340. doi: 10.1002/adhm.202402340. Epub 2024 Oct 1.
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Platelet Vesicles Synergetic with Biosynthetic Cellulose Aerogels for Ultra-Fast Hemostasis and Wound Healing.血小板囊泡与生物合成纤维素气凝胶协同作用实现超快速止血和伤口愈合。
Adv Healthc Mater. 2024 Jul;13(17):e2304523. doi: 10.1002/adhm.202304523. Epub 2024 Feb 28.
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An Adhesive/Anti-Adhesive Janus Tissue Patch for Efficient Closure of Bleeding Tissue with Inhibited Postoperative Adhesion.一种具有粘合/抗粘合双效的组织贴片，可有效封闭出血组织，并抑制术后粘连。
Adv Sci (Weinh). 2023 Jul;10(21):e2301427. doi: 10.1002/advs.202301427. Epub 2023 May 12.
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Current insights on haemorrhagic complications in percutaneous nephrolithotomy.经皮肾镜取石术出血并发症的最新见解
Asian J Urol. 2022 Jan;9(1):81-93. doi: 10.1016/j.ajur.2021.05.007. Epub 2021 May 29.
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Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue.受藤壶胶启发的糊剂实现快速止血且不依赖于凝血。
Nat Biomed Eng. 2021 Oct;5(10):1131-1142. doi: 10.1038/s41551-021-00769-y. Epub 2021 Aug 9.
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Metabolic Profiling of a Porcine Combat Trauma-Injury Model Using NMR and Multi-Mode LC-MS Metabolomics-A Preliminary Study.使用核磁共振和多模式液相色谱-质谱代谢组学对猪战斗创伤损伤模型进行代谢谱分析——一项初步研究
Metabolites. 2020 Sep 16;10(9):373. doi: 10.3390/metabo10090373.
9
Fluid resuscitation in trauma: what are the best strategies and fluids?创伤中的液体复苏：最佳策略和液体是什么？
Int J Emerg Med. 2019 Dec 4;12(1):38. doi: 10.1186/s12245-019-0253-8.
10
Acute Kidney Injury in Severe Trauma Patients; a Record-Based Retrospective Study.严重创伤患者的急性肾损伤；一项基于记录的回顾性研究。
Adv J Emerg Med. 2019 Mar 27;3(3):e22. doi: 10.22114/ajem.v0i0.141. eCollection 2019 Summer.

本文引用的文献

1
What are the ten new commandments in severe polytrauma management?严重多发伤管理的十大新戒律是什么？
World J Emerg Med. 2010;1(2):85-92.
2
Restrictive fluid resuscitation in combination with damage control resuscitation: time for adaptation.限制液体复苏联合损伤控制性复苏：适应的时机。
J Trauma Acute Care Surg. 2012 Sep;73(3):674-8. doi: 10.1097/TA.0b013e318265ce1f.
3
Validation of the pulse rate over pressure evaluation index as a detector of early occult hemorrhage: a prospective observational study.脉搏率超过压力评估指数验证作为早期隐匿性出血的探测器：一项前瞻性观察研究。
J Trauma Acute Care Surg. 2012 Jul;73(1):286-8. doi: 10.1097/TA.0b013e318253b52e.
4
Management of major trauma haemorrhage: treatment priorities and controversies.严重创伤性出血的处理：治疗重点和争议。
Br J Haematol. 2011 Dec;155(5):537-48. doi: 10.1111/j.1365-2141.2011.08885.x. Epub 2011 Oct 21.
5
Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial.低血压复苏策略可减少创伤性失血性休克患者的输血需求及严重术后凝血功能障碍：一项随机对照试验的初步结果
J Trauma. 2011 Mar;70(3):652-63. doi: 10.1097/TA.0b013e31820e77ea.
6
Utility of the shock index in predicting mortality in traumatically injured patients.休克指数在预测创伤患者死亡率中的应用。
J Trauma. 2009 Dec;67(6):1426-30. doi: 10.1097/TA.0b013e3181bbf728.
7
Battlefield resuscitation.战地复苏。
Curr Opin Crit Care. 2009 Dec;15(6):527-35. doi: 10.1097/MCC.0b013e32833190c3.
8
An evaluation of the impact of apheresis platelets used in the setting of massively transfused trauma patients.对大量输血创伤患者使用单采血小板的影响评估。
J Trauma. 2009 Apr;66(4 Suppl):S77-84; discussion S84-5. doi: 10.1097/TA.0b013e31819d8936.
9
Preconditions of hemostasis in trauma: a review. The influence of acidosis, hypocalcemia, anemia, and hypothermia on functional hemostasis in trauma.创伤止血的前提条件：综述。酸中毒、低钙血症、贫血和低温对创伤中功能性止血的影响。
J Trauma. 2008 Oct;65(4):951-60. doi: 10.1097/TA.0b013e318187e15b.
10
The coagulopathy of trauma: a review of mechanisms.创伤性凝血病：机制综述
J Trauma. 2008 Oct;65(4):748-54. doi: 10.1097/TA.0b013e3181877a9c.