Yoon Bo Sung, Kim You Shin, Seong Seok Ju, Song Taejong, Kim Mi-La, Kim Mi Kyoung, Paek Jin Young
Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
Fertility Center of CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
Eur J Obstet Gynecol Reprod Biol. 2014 May;176:34-8. doi: 10.1016/j.ejogrb.2014.02.025. Epub 2014 Feb 20.
Single-port access (SPA) laparoscopic ovarian cystectomy has been reported as a comparable procedure to conventional laparoscopy in terms of operative outcomes. However, whether ovarian function after SPA laparoscopic surgery is similar to conventional laparoscopy is questioned due to the limitations in moving instruments. The aim of this study was to evaluate whether the reduced port number affects the ovarian reserve after laparoscopic ovarian cystectomy.
This was a randomized controlled trial of 87 women with benign ovarian cyst, who attended a university hospital and were scheduled for laparoscopic ovarian cystectomy. Women were randomized to SPA, two-port access (TPA), or four-port access (FPA) laparoscopic groups. The primary outcome was the serum anti-Müllerian hormone (AMH) levels: preoperative, 1 week, 1 month and 3 months after the operation. Secondary outcomes were operative outcomes.
The mean serum AMH levels of preoperative, 1 week, 1 month and 3 months after laparoscopy were 4.4±2.9, 2.7±2.2, 2.3±1.9, and 2.5±1.5ng/mL (in the SPA group), 3.6±2.5, 2.3±2.2, 2.6±3.2, and 2.7±2.6ng/mL (in the TPA group), and 3.9±3.2, 2.4±2.1, 2.5±2.0, and 2.8±2.2ng/mL (in the FPA group), respectively. There was no statistically significant difference in the serial change of AMH levels among the SPA, TPA and FPA groups.
The laparoscopic ovarian cystectomy with reduced port number does not affect the serial change of ovarian reserve. The SPA or TPA laparoscopy may be the alternative method to conventional laparoscopy in terms of ovarian reserve.
据报道，单孔腹腔镜卵巢囊肿切除术在手术效果方面与传统腹腔镜手术相当。然而，由于操作器械移动受限，单孔腹腔镜手术后卵巢功能是否与传统腹腔镜手术相似受到质疑。本研究的目的是评估减少穿刺孔数量是否会影响腹腔镜卵巢囊肿切除术后的卵巢储备功能。
这是一项针对87例患有良性卵巢囊肿的女性的随机对照试验，这些女性在大学医院就诊并计划接受腹腔镜卵巢囊肿切除术。将女性随机分为单孔腹腔镜组（SPA）、两孔腹腔镜组（TPA）或四孔腹腔镜组（FPA）。主要结局指标是术前、术后1周、1个月和3个月时血清抗苗勒管激素（AMH）水平。次要结局指标是手术效果。
腹腔镜术后术前、1周、1个月和3个月时，SPA组血清AMH平均水平分别为4.4±2.9、2.7±2.2、2.3±1.9和2.5±1.5ng/mL；TPA组分别为3.6±2.5、2.3±2.2、2.6±3.2和2.7±2.6ng/mL；FPA组分别为3.9±3.2、2.4±... 显示全部
