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英国骨科肩关节外科医生对安慰剂手术的态度和看法。

Attitudes and beliefs about placebo surgery among orthopedic shoulder surgeons in the United Kingdom.

作者信息

Wartolowska Karolina, Beard David J, Carr Andrew J

机构信息

Botnar Institute of Musculoskeletal Sciences, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.

出版信息

PLoS One. 2014 Mar 14;9(3):e91699. doi: 10.1371/journal.pone.0091699. eCollection 2014.

Abstract

OBJECTIVES

To survey surgeons on their beliefs and attitudes towards the use of placebo in surgery.

METHODS

British orthopedic shoulder surgeons, attending a national conference in the United Kingdom, were asked to complete a self-report online questionnaire about their beliefs and attitudes towards the use of placebo related to surgical intervention. The survey included questions about ethical issues, the mechanism of placebo effects, and any concerns regarding its use.

RESULTS

100 surgeons who participated in the survey believed that placebo surgery is ethically acceptable (96%), especially as a part of a clinical trial (46%). Respondents thought that a placebo effect in surgery is real i.e. has a scientific basis (92%), that placebo can be therapeutically beneficial (77%), and that it involves psychological mechanisms (96%). Over half of the respondents (58%) have used a surgical procedure with a significant placebo component at least once in their professional career. Their main concern about placebo use in surgery was that it might involve an element of deception.

CONCLUSIONS AND IMPLICATIONS

Surgeons generally agreed that a placebo component to surgical intervention might exist. They also supported placebo use in clinical trials and considered it ethical, providing it does not involve deception of patients. More studies are needed, particularly among other surgical specialties and with larger numbers of participants, to better understand the use of placebo in surgery.

摘要

目的

调查外科医生对手术中使用安慰剂的看法和态度。

方法

邀请参加英国全国性会议的英国骨科肩部外科医生,完成一份关于他们对与手术干预相关的安慰剂使用的看法和态度的在线自填问卷。该调查包括有关伦理问题、安慰剂效应机制以及对其使用的任何担忧的问题。

结果

参与调查的100名外科医生认为安慰剂手术在伦理上是可以接受的(96%),特别是作为临床试验的一部分(46%)。受访者认为手术中的安慰剂效应是真实的,即有科学依据(92%),安慰剂具有治疗益处(77%),并且涉及心理机制(96%)。超过一半的受访者(58%)在其职业生涯中至少有一次使用过具有显著安慰剂成分的手术程序。他们对手术中使用安慰剂的主要担忧是这可能涉及欺骗因素。

结论与启示

外科医生普遍认为手术干预中可能存在安慰剂成分。他们也支持在临床试验中使用安慰剂,并认为只要不涉及欺骗患者,就是符合伦理的。需要进行更多研究,特别是在其他外科专业领域以及有更多参与者的情况下,以更好地了解手术中安慰剂的使用情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35ce/3954758/2284a0487d70/pone.0091699.g001.jpg

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