College of Health and Biomedicine, Victoria University, PO Box 14428, Melbourne, 8001, Australia,
Eur J Appl Physiol. 2014 Jun;114(6):1321-32. doi: 10.1007/s00421-014-2866-1. Epub 2014 Mar 16.
The present study evaluated the effects of creatine monohydrate (CrM) consumption post-exercise on body composition and muscle strength in middle to older males following a 12-week resistance training program.
In a double-blind, randomized trial, 20 males aged between 55 and 70 years were randomly assigned to consume either CrM-carbohydrate (CHO) [20 g days(-1) CrM + 5 g days(-1) CHO × 7 days, then 0.1 g kg(-1) CrM + 5 g CHO on training days (average dosage of ~8.8 g)] or placebo CHO (20 g days(-1) CHO × 7 days, then 5 g CHO on training days) while participating in a high intensity resistance training program [3 sets × 10 repetitions at 75% of 1 repetition maximum (1RM)], 3 days weeks(-1) for 12 weeks. Following the initial 7-day "loading" phase, participants were instructed to ingest their supplement within 60 min post-exercise. Body composition and muscle strength measurements, blood collection and vastus lateralis muscle biopsy were completed at 0, 4, 8 and 12 weeks of the supplement and resistance training program.
A significant time effect was observed for 1RM bench press (p = 0.016), leg press (p = 0.012), body mass (p = 0.03), fat-free mass (p = 0.005) and total myofibrillar protein (p = 0.005). A trend for larger muscle fiber cross-sectional area in the type II fibers compared to type I fibers was observed following the 12-week resistance training (p = 0.08). No supplement interaction effects were observed.
Post-exercise ingestion of creatine monohydrate does not provide greater enhancement of body composition and muscle strength compared to resistance training alone in middle to older males.
本研究评估了在 12 周抗阻训练计划后,运动后补充一水肌酸(CrM)对中年至老年男性的身体成分和肌肉力量的影响。
在一项双盲、随机试验中,20 名年龄在 55 至 70 岁之间的男性被随机分为两组,分别补充 CrM-碳水化合物(CHO)[20 g·天(-1)CrM+5 g·天(-1)CHO×7 天,然后 0.1 g·kg(-1)CrM+5 g CHO 在训练日(平均剂量约 8.8 g)]或安慰剂 CHO(20 g·天(-1)CHO×7 天,然后在训练日补充 5 g CHO),同时参加高强度抗阻训练计划[3 组×10 次,重复 75%的 1 次最大重复次数(1RM)],每周 3 天,持续 12 周。在最初的 7 天“加载”阶段后,参与者被指示在运动后 60 分钟内服用补充剂。在补充剂和抗阻训练计划的 0、4、8 和 12 周时,完成身体成分和肌肉力量测量、血液采集和股外侧肌活检。
1RM 卧推(p=0.016)、腿推(p=0.012)、体重(p=0.03)、去脂体重(p=0.005)和总肌原纤维蛋白(p=0.005)均观察到显著的时间效应。在 12 周抗阻训练后,观察到 II 型纤维的肌纤维横截面积比 I 型纤维有更大的趋势(p=0.08)。未观察到补充剂相互作用的影响。
与单独进行抗阻训练相比,运动后补充一水肌酸并不能在中年至老年男性中提供更好的身体成分和肌肉力量的增强效果。