Naimi-Akbar Aron, Sandborgh-Englund Gunilla, Ekbom Anders, Ekstrand Jan, Näsman Peggy, Montgomery Scott
J Perinat Med. 2014 Sep;42(5):655-61. doi: 10.1515/jpm-2013-0270.
Dental personnel are exposed to mercury when using dental amalgam. This exposure constitutes a potential hazard to offspring of women working in dentistry. The present study examined increased mortality risk in offspring of mothers working in dentistry.
Mortality was compared between sons of dental personnel and sons of nondental health-care personnel. Hazard ratios were calculated for three decades (1960s-1980s), when the magnitude of mercury exposure in dentistry was likely to have varied.
During the 1960s, there was a statistically significant increase in the risk of neonatal mortality for sons of dental nurses when compared with sons of assistant nurses: hazard ratio (HR) 1.82 (95% confidence interval, CI: 1.04-3.22). There was no increased risk in the subsequent decades, but a trend test demonstrated a consistent decrease in the risk over the three decades: HR for trend 0.63 (95% CI: 0.44-0.90). The raised mortality risk was limited to neonatal mortality. The comparison between dentists and physicians had insufficient statistical power.
There is no increased mortality risk among sons of female dentists after the 1960s. Although the results should be interpreted with caution, they suggest a modestly raised risk of neonatal mortality, during the 1960s, when exposure to mercury was thought to be highest.
牙科工作人员在使用银汞合金时会接触到汞。这种接触对从事牙科工作的女性的后代构成潜在危害。本研究调查了从事牙科工作的母亲的后代死亡风险增加的情况。
比较牙科工作人员的儿子与非牙科医护人员的儿子的死亡率。计算了三个十年（20世纪60年代至80年代）的风险比，当时牙科汞接触量可能有所不同。
在20世纪60年代，与助理护士的儿子相比，牙科护士的儿子新生儿死亡风险有统计学显著增加：风险比（HR）为1.82（95%置信区间，CI：1.04 - 3.22）。在随后几十年中风险没有增加，但趋势检验表明在这三个十年中风险持续下降：趋势风险比为0.63（95%CI：0.44 - 0.90）。升高的死亡风险仅限于新生儿死亡。牙医与医生之间的比较统计效力不足。
20世纪60年代以后，女牙医的儿子中没有增加的死亡风险。尽管对结果的解释应谨慎，但结果表明在20世纪60年代汞接触被认为最高时，新生儿死亡风险略有升高。
