西梅诺苷A，一种来自准噶尔丝石竹（Gypsophila simonii Hub.-Mor.）的新型三萜皂苷

Simenoside A, a new triterpenoid saponin from Gypsophila simonii Hub.-Mor.

作者信息

Arslan Idris

机构信息

Pamukkale University, Faculty of Technology, Biomedical Engineering, TR-20017 Denizli, (phone: +90-258-2963026; fax: +90-258-2963263).

出版信息

Chem Biodivers. 2014 Mar;11(3):445-50. doi: 10.1002/cbdv.201300118.

DOI:10.1002/cbdv.201300118

PMID:24634074

Abstract

Saponins are amphiphilic glycoconjugates which give soap-like foams in H2 O. A new triterpenoid saponin, simenoside A (1), based on gypsogenin aglycone, and the known saponin 2 were isolated from Gypsophila simonii Hub.-Mor. The structure of the new saponin was elucidated as 3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosylgypsogenin 28-O-β-D-glucopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→2)-β-D-xylopyranosyl-(1→4)]-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranosyl ester on the basis of extensive spectral analyses and chemical evidence. Saponins 1 and 2 were isolated from G. simonii for the first time.

摘要

皂苷是两亲性糖缀合物，在水中会产生类似肥皂的泡沫。从丝石竹（Gypsophila simonii Hub.-Mor.）中分离出一种基于绞股蓝皂苷元苷元的新三萜皂苷——丝石竹皂苷A（1）和已知皂苷2。通过广泛的光谱分析和化学证据，新皂苷的结构被阐明为3-O-β-D-吡喃半乳糖基-(1→2)-[β-D-吡喃木糖基-(1→3)]-β-D-吡喃葡萄糖醛酸基绞股蓝皂苷元28-O-β-D-吡喃葡萄糖基-(1→3)-[β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃木糖基-(1→4)]-α-L-吡喃鼠李糖基-(1→2)-β-D-吡喃岩藻糖基酯。皂苷1和2首次从丝石竹中分离得到。