包涵体肌炎所致吞咽困难：病例报告及文献复习
Dysphagia due to inclusion body myositis: case presentation and review of the literature.
作者信息
Ko Ellen H, Rubin Adam D
机构信息
Lakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, St. Clair Shores, Michigan, USA.
Lakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, St. Clair Shores, Michigan, USA Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA
出版信息
Ann Otol Rhinol Laryngol. 2014 Sep;123(9):605-8. doi: 10.1177/0003489414525588. Epub 2014 Mar 14.
OBJECTIVE
This report aimed to present a case of inclusion body myositis presenting with dysphagia and to review the literature.
METHODS
Case report and literature review.
RESULTS
Inclusion body myositis is a chronic progressive acquired myopathy, uniquely distinguished by its selective muscle involvement, normal or moderately elevated muscle enzyme concentrations, and a progressive corticosteroid-resistant course. Compared to other inflammatory myopathies, the esophagus is the most commonly involved organ. Specifically, upper esophageal sphincter dysfunction often occurs. Dysphagia may be the only symptom at the time of presentation.
CONCLUSION
Unlike other inflammatory myopathies, dysphagia in inclusion body myositis is steroid resistant. Management can be difficult. The otolaryngologist must consider underlying neuromuscular processes when evaluating the patient presenting with oropharyngeal dysphagia.
目的
本报告旨在介绍一例以吞咽困难为表现的包涵体肌炎病例并进行文献复习。
方法
病例报告及文献复习。
结果
包涵体肌炎是一种慢性进行性获得性肌病，其独特之处在于选择性肌肉受累、肌肉酶浓度正常或中度升高以及对皮质类固醇治疗呈进行性抵抗。与其他炎性肌病相比，食管是最常受累的器官。具体而言，食管上括约肌功能障碍常发生。吞咽困难可能是就诊时唯一的症状。
结论
与其他炎性肌病不同，包涵体肌炎中的吞咽困难对类固醇治疗耐药。治疗可能困难。耳鼻喉科医生在评估有口咽吞咽困难的患者时必须考虑潜在的神经肌肉病变。
Zotero 插件