Darrow D H, Hoffman H T, Barnes G J, Wiley C A
Division of Otolaryngology-Head and Neck Surgery, University of California, San Diego School of Medicine.
Arch Otolaryngol Head Neck Surg. 1992 Mar;118(3):313-7. doi: 10.1001/archotol.1992.01880030103021.
Inclusion body myositis is an inflammatory myopathy in which dysphagia has been considered a rare finding. However, recent literature finds dysphagia an increasingly common symptom as more cases of inclusion body myositis are identified. Unlike some inflammatory myopathic disorders, inclusion body myositis is resistant to treatment with corticosteroids, and therefore, the otolaryngologist may be consulted regarding surgical options for relief of dysphagia. A patient is described in whom severe progressive dysphagia associated with inclusion body myositis developed. Impaired pharyngeal wall motion and cricopharyngeal achalasia were demonstrated by videofluoroscopic evaluation, and the patient was successfully treated by cricopharyngeal myotomy. The pathophysiologic nature of inclusion body myositis and the mechanisms of cervical dysphagia in the inflammatory myopathies are reviewed.
包涵体肌炎是一种炎性肌病，其中吞咽困难被认为是一种罕见表现。然而，近期文献发现随着更多包涵体肌炎病例被确诊，吞咽困难正成为越来越常见的症状。与某些炎性肌病不同，包涵体肌炎对皮质类固醇治疗有抵抗性，因此，可能会就缓解吞咽困难的手术选择咨询耳鼻喉科医生。本文描述了一名患有与包涵体肌炎相关的严重进行性吞咽困难的患者。通过视频荧光透视评估证实了咽壁运动受损和环咽肌失弛缓，该患者通过环咽肌肌切开术获得成功治疗。本文对包涵体肌炎的病理生理性质以及炎性肌病中颈部吞咽困难的机制进行了综述。
