Son Seungnam, Choi Dae Seob, Oh Min Kyun, Kim Soo-Kyoung, Kang Heeyoung, Park Ki-Jong, Choi Nack-Cheon, Kwon Oh-Young, Lim Byeong Hoon
Department of Neurology, Gyeongsang National University School of Medicine, Jinju, Korea Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea.
Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.
J Neurointerv Surg. 2015 Apr;7(4):238-44. doi: 10.1136/neurintsurg-2014-011141. Epub 2014 Mar 14.
The feasibility, safety and effectiveness of emergency carotid artery stenting (eCAS) in patients with acute ischemic stroke (AIS) due to proximal internal carotid artery (ICA) stenosis or occlusion are still controversial. In this study we analyzed our experience with eCAS in patients with AIS.
Twenty-two eCAS procedures for proximal ICA stenosis or occlusion were performed in 22 patients at our institution between January 2011 and November 2013. The mean time from stroke symptom onset to presentation was 204 min (range 50-630 min) and the mean initial score on the National Institutes of Health Stroke Scale (NIHSS) was 12.55 (range 5-23). Ten patients had total occlusion of the proximal ICA and the remaining 12 patients had near total occlusion or severe stenosis (mean degree 90.7%, range 80-100%). Eleven patients also had tandem occlusion on the more distal intracranial arteries.
Successful stent insertion was achieved in all patients and additional thrombectomy using a Solitaire stent or Penumbra aspiration catheter achieved a Thrombolysis In Cerebral Infarction grade of more than 2a in all patients with distal tandem occlusion. Procedure-related complications occurred in one patient (cerebral hyperperfusion syndrome) who recovered successfully. The mean NIHSS score at discharge was 3.55 (range 0-18). The mean modified Rankin Scale score at 3 months was 1 ± 1.67 (range 0-6).
eCAS in patients with AIS due to proximal ICA stenosis or occlusion appears to be a technically feasible and effective method for achieving good clinical outcomes.
对于因颈内动脉(ICA)近端狭窄或闭塞导致的急性缺血性卒中(AIS)患者,急诊颈动脉支架置入术(eCAS)的可行性、安全性和有效性仍存在争议。在本研究中,我们分析了我们在AIS患者中进行eCAS的经验。
2011年1月至2013年11月期间,我们机构对22例患者进行了22次针对ICA近端狭窄或闭塞的eCAS手术。从卒中症状发作到就诊的平均时间为204分钟(范围50 - 630分钟),美国国立卫生研究院卒中量表(NIHSS)的平均初始评分为12.55(范围5 - 23)。10例患者ICA近端完全闭塞,其余12例患者近乎完全闭塞或严重狭窄(平均程度90.7%,范围80 - 100%)。11例患者在更远端的颅内动脉也存在串联闭塞。
所有患者均成功置入支架,对于所有存在远端串联闭塞的患者,使用Solitaire支架或Penumbra抽吸导管进行的额外血栓切除术使脑梗死溶栓分级达到2a级以上。1例患者发生与手术相关的并发症(脑过度灌注综合征),但已成功康复。出院时NIHSS评分的平均值为3.55(范围0 - 18)。3个月时改良Rankin量表评分的平均值为1 ± 1.67(范围)。
对于因ICA近端狭窄或闭塞导致的AIS患者,eCAS似乎是一种技术上可行且有效的方法,可取得良好的临床结果。