• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Bichalcophenes: A Concise Synthesis of Formyl Ester- and Cyano Ester-Substituted Bithiophenes, Bifurans, and Furanothiophenes.二卤代苯并噻吩类化合物:甲酰基酯和氰基酯取代的联噻吩、双呋喃和呋喃并噻吩的简洁合成法
J Heterocycl Chem. 2010 Jan 8;47(1):167-170. doi: 10.1002/jhet.295.
2
SYNTHESIS OF NOVEL BITHIOPHENE-SUBSTITUTED HETEROCYCLES BEARING CARBONITRILE GROUPS.含腈基的新型联噻吩取代杂环化合物的合成
Synth Commun. 2011 Jan 1;41(3):319-330. doi: 10.1080/00397910903537364.
3
Ring expansion-annulation strategy for the synthesis of substituted azulenes and oligoazulenes. 2. Synthesis of azulenyl halides, sulfonates, and azulenylmetal compounds and their application in transition-metal-mediated coupling reactions.用于合成取代薁和低聚薁的扩环-环化策略。2. 薁基卤化物、磺酸盐和薁基金属化合物的合成及其在过渡金属介导的偶联反应中的应用。
J Org Chem. 2004 Dec 10;69(25):8652-67. doi: 10.1021/jo048698c.
4
Intramolecular interactions between chalcogen atoms: organoseleniums derived from 1-bromo-4-tert-butyl-2,6-di(formyl)benzene.硫族元素原子间的分子内相互作用:源自1-溴-4-叔丁基-2,6-二(甲酰基)苯的有机硒化合物
J Org Chem. 2005 Apr 29;70(9):3693-704. doi: 10.1021/jo0478656.
5
Syntheses of 2- and 3-Substituted Morpholine Congeners via Ring Opening of 2-Tosyl-1,2-Oxazetidine.通过 2-对甲苯磺酰基-1,2-噁唑烷的开环反应合成 2-和 3-取代的吗啡啉同系物。
J Org Chem. 2023 May 5;88(9):6182-6191. doi: 10.1021/acs.joc.3c00207. Epub 2023 Apr 26.
6
Unprecedented negishi coupling at C-br in the presence of a stannyl group as a convenient approach to pyridinylstannanes and their application in liquid crystal synthesis.在存在锡烷基的情况下,在C-溴处进行前所未有的根岸偶联,这是一种制备吡啶基锡烷的便捷方法及其在液晶合成中的应用。
J Org Chem. 2008 Feb 1;73(3):830-9. doi: 10.1021/jo701812t. Epub 2008 Jan 8.
7
Novel 4-substituted phenyl-2,2'-bichalcophenes and aza-analogs as antibacterial agents: a structural activity relationship.新型4-取代苯基-2,2'-双硫杂苯及其氮杂类似物作为抗菌剂:构效关系
Drug Des Devel Ther. 2013 Mar 22;7:185-93. doi: 10.2147/DDDT.S42073. Print 2013.
8
Total syntheses of (+/-)-cis-trikentrin A and (+/-)-cis-trikentrin B via electrocyclic ring closures of 2,3-divinylpyrrolines.通过2,3-二乙烯基吡咯啉的电环化闭环反应全合成(±)-顺式三锥星烷A和(±)-顺式三锥星烷B
Org Lett. 2006 Jul 20;8(15):3403-6. doi: 10.1021/ol061259a.
9
Total Synthesis of (±)-Nisamycin.(±)-尼沙霉素的全合成
J Org Chem. 1999 Jul 9;64(14):5053-5061. doi: 10.1021/jo990413m.
10
[Optimization of alkaline hydrolysis based on the side chain of diethyl ester 4-amino-N-formyl-N, N-dideazatetrahydrofolic acid].[基于4-氨基-N-甲酰基-N,N-二去氮四氢叶酸二乙酯侧链的碱性水解优化]
Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Aug 18;49(4):714-718.

引用本文的文献

1
Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity.研究呋咱甲脒结构修饰对其与 DNA 小沟结合和抗原生动物活性的影响。
Eur J Med Chem. 2023 Apr 5;252:115287. doi: 10.1016/j.ejmech.2023.115287. Epub 2023 Mar 20.
2
Engineered modular heterocyclic-diamidines for sequence-specific recognition of mixed AT/GC base pairs at the DNA minor groove.用于在DNA小沟中对混合的AT/GC碱基对进行序列特异性识别的工程化模块化杂环二脒。
Chem Sci. 2021 Nov 2;12(48):15849-15861. doi: 10.1039/d1sc04720e. eCollection 2021 Dec 15.
3
Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity.吲哚和苯并咪唑双硫杂菲:合成、DNA结合及抗寄生虫活性
Eur J Med Chem. 2018 Jan 1;143:1590-1596. doi: 10.1016/j.ejmech.2017.10.056. Epub 2017 Oct 22.
4
The Thiophene "Sigma-Hole" as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove.噻吩“sigma-hole”作为预组织的概念,用于特异性识别 DNA 小沟中的 G⋅C 碱基对。
Chemistry. 2016 Oct 17;22(43):15404-15412. doi: 10.1002/chem.201603422. Epub 2016 Sep 14.

本文引用的文献

1
Carbon dioxide induced phase switching for homogeneous-catalyst recycling.二氧化碳诱导的均相催化剂循环相切换
Angew Chem Int Ed Engl. 2009;48(8):1472-4. doi: 10.1002/anie.200804729.
2
A light-resistant organic sensitizer for solar-cell applications.一种用于太阳能电池应用的耐光有机敏化剂。
Angew Chem Int Ed Engl. 2009;48(9):1576-80. doi: 10.1002/anie.200804719.
3
Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors.基于噻吩嘧啶的双重 EGFR/ErbB-2 抑制剂。
Bioorg Med Chem Lett. 2009 Feb 1;19(3):817-20. doi: 10.1016/j.bmcl.2008.12.011. Epub 2008 Dec 7.
4
Organic dyes containing furan moiety for high-performance dye-sensitized solar cells.用于高性能染料敏化太阳能电池的含呋喃部分的有机染料。
Org Lett. 2009 Jan 1;11(1):97-100. doi: 10.1021/ol8025236.
5
Amidine catalysed O- to C-carboxyl transfer of heterocyclic carbonate derivatives.脒催化杂环碳酸酯衍生物的O-到C-羧基转移。
Org Biomol Chem. 2008 Aug 21;6(16):2900-7. doi: 10.1039/b805850d. Epub 2008 Jun 16.
6
Amino(oligo)thiophene-based environmentally sensitive biomembrane chromophores.基于氨基(寡聚)噻吩的环境敏感生物膜发色团。
J Org Chem. 2008 Sep 5;73(17):6587-94. doi: 10.1021/jo800852h. Epub 2008 Jul 30.
7
Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.有机阳离子对四链体DNA的结构特异性识别:形状、取代基和电荷的影响
Biophys Chem. 2007 Mar;126(1-3):140-53. doi: 10.1016/j.bpc.2006.06.006. Epub 2006 Jun 20.
8
Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles.7-[(2,4-二氯-5-甲氧基苯基)氨基]-2-杂芳基噻吩并[3,2-b]吡啶-6-腈对Src激酶活性的抑制作用
Bioorg Med Chem Lett. 2005 Nov 1;15(21):4681-4. doi: 10.1016/j.bmcl.2005.07.061.
9
Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test.用简单荧光试验检测布氏锥虫对含砷药物的耐药性。
Lancet. 2005;366(9484):486-7. doi: 10.1016/S0140-6736(05)66793-1.
10
Design, synthesis, linear, and nonlinear optical properties of conjugated (porphinato)zinc(II)-based donor-acceptor chromophores featuring nitrothiophenyl and nitrooligothiophenyl electron-accepting moieties.基于(卟啉基)锌(II)的供体-受体发色团的设计、合成、线性和非线性光学性质,该发色团具有硝基噻吩基和硝基低聚噻吩基电子接受部分。
J Am Chem Soc. 2005 Jul 13;127(27):9710-20. doi: 10.1021/ja0402553.

二卤代苯并噻吩类化合物:甲酰基酯和氰基酯取代的联噻吩、双呋喃和呋喃并噻吩的简洁合成法

Bichalcophenes: A Concise Synthesis of Formyl Ester- and Cyano Ester-Substituted Bithiophenes, Bifurans, and Furanothiophenes.

作者信息

Farahat Abdelbasset A, Kumar Arvind, Barghash Alaa El-Din M, Goda Fatma E, Eisa Hassan M, Boykin David W

机构信息

Department of Chemistry, Georgia State University, Atlanta, Georgia 30303 ; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, Egypt.

Department of Chemistry, Georgia State University, Atlanta, Georgia 30303.

出版信息

J Heterocycl Chem. 2010 Jan 8;47(1):167-170. doi: 10.1002/jhet.295.

DOI:10.1002/jhet.295
PMID:24634543
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3949757/
Abstract

Syntheses of new formyl ester- and cyano ester-substituted bithiophenes, bifurans, and furanothiophenes in good yield are described. The key synthetic step uses Stille coupling of appropriately substituted bromo 5-ring heterocycles with stannyl-substituted 5-ring heterocycles.

摘要

本文描述了新型甲酰酯和氰基酯取代的联噻吩、双呋喃和呋喃并噻吩的合成,产率良好。关键的合成步骤是将适当取代的溴代五环杂环与锡基取代的五环杂环进行Stille偶联。