Farahat Abdelbasset A, Kumar Arvind, Barghash Alaa El-Din M, Goda Fatma E, Eisa Hassan M, Boykin David W
Department of Chemistry, Georgia State University, Atlanta, Georgia 30303 ; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, Egypt.
Department of Chemistry, Georgia State University, Atlanta, Georgia 30303.
J Heterocycl Chem. 2010 Jan 8;47(1):167-170. doi: 10.1002/jhet.295.
Syntheses of new formyl ester- and cyano ester-substituted bithiophenes, bifurans, and furanothiophenes in good yield are described. The key synthetic step uses Stille coupling of appropriately substituted bromo 5-ring heterocycles with stannyl-substituted 5-ring heterocycles.
本文描述了新型甲酰酯和氰基酯取代的联噻吩、双呋喃和呋喃并噻吩的合成,产率良好。关键的合成步骤是将适当取代的溴代五环杂环与锡基取代的五环杂环进行Stille偶联。