Chen Hui, Fan Ying-Chuan, He Qi-Hong, Wu Xiao-Yun, Wei Min, Eichner June E, Farris Bradley K, Hildebrand P Lloyd, Lei Chun-Tao, Wu Shu-Hua, Yang Jing-Yun
Department of Ophthalmology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China ; Institute of Laboratory Animals, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China, Luzhou 646000, Sichuan Province, China.
Institute of Laboratory Animals, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China, Luzhou 646000, Sichuan Province, China.
Int J Ophthalmol. 2014 Feb 18;7(1):139-44. doi: 10.3980/j.issn.2222-3959.2014.01.26. eCollection 2014.
To study the trends of major causes of visual impairment (VI) in adults in Sichuan, China and evaluate the effect of aging on the trends.
We used data from the National Sample Survey on Disabilities (NSSD) in Sichuan province conducted in 1987 and 2006. The age-adjusted prevalence of major causes of VI and the prevalence stratified by age in each cause were calculated and compared. The association between age and each cause of VI was also analyzed.
Retinal disease increased and became the second leading cause of VI in 2006 while blinding trachoma decreased markedly. Cataract and non-trachomatous corneal diseases were among the leading causes of VI in both years. We found associations between age and causes of VI, with age showing the strongest association with cataract and relatively lower associations with other causes.
In the last two decades, dramatic changes occurred in the major causes of VI with significantly increased retinal disease and decreased blinding trachoma. Aging of the population might be an important factor accounting for the changed trends of VI. Understanding the prevalence of VI, its major causes and trends over time can assist in prioritizing and developing effective interventional strategies and monitoring their impact.
研究中国四川省成年人视力损害（VI）主要病因的变化趋势，并评估老龄化对这些趋势的影响。
我们使用了1987年和2006年在四川省进行的全国残疾人抽样调查（NSSD）的数据。计算并比较了VI主要病因的年龄调整患病率以及各病因按年龄分层的患病率。还分析了年龄与每种VI病因之间的关联。
视网膜疾病患病率上升，在2006年成为VI的第二大主要病因，而致盲性沙眼显著减少。白内障和非沙眼性角膜疾病在这两年均为VI的主要病因。我们发现年龄与VI病因之间存在关联，年龄与白内障的关联最强，与其他病因的关联相对较弱。
在过去二十年中，VI的主要病因发生了巨大变化，视网膜疾病显著增加，致盲性沙眼减少。人口老龄化可能是导致VI趋势变化的一个重要因素。了解VI的患病率、主要病因及其随时间的变化趋势有助于确定优先事项并制定有效的干预策略，以及监测其影响。
