Malik M, Camm A J
Department of Cardiological Sciences, St. George's Hospital Medical School, London, United Kingdom.
Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):2101-9. doi: 10.1111/j.1540-8159.1988.tb06357.x.
Different computer models have been developed in order to study various aspects of cardiac electrophysiological processes. These models can be classified according to many parameters and also in respect to their application areas. One group of the models is devoted to computer simulation of cardiac rhythm disturbances and to reproduction of interactions between the heart and an artificial pulse generator. This report overviews the recent models of arrhythmias and heart-pacemaker interaction. Special attention is paid to (1) functioning of fundamental model elements, (2) structure of the heart model, (3) pacemaker models, and (4) forms of results offered by simulation experiments. Existing models are classified and compared. To illustrate the medical capability of rhythm and pacemaker models, three computational experiments are presented with model atrioventricular reentry tachycardia and reentry tachycardia mediated by a DDD pacemaker. Future development and utilization of arrhythmia and pacemaker models are briefly discussed.
为了研究心脏电生理过程的各个方面，已经开发了不同的计算机模型。这些模型可以根据许多参数进行分类，也可以根据其应用领域进行分类。其中一组模型致力于心脏节律紊乱的计算机模拟以及心脏与人工脉冲发生器之间相互作用的再现。本报告概述了最近的心律失常和心脏起搏器相互作用模型。特别关注以下方面：（1）基本模型元件的功能，（2）心脏模型的结构，（3）起搏器模型，以及（4）模拟实验提供的结果形式。对现有模型进行了分类和比较。为了说明节律和起搏器模型的医学应用能力，展示了三个关于房室折返性心动过速和由DDD起搏器介导的折返性心动过速模型的计算实验。简要讨论了心律失常和起搏器模型的未来发展与应用。
