Hiraishi Yoshihisa, Iikura Motoyasu, Kogure Yoshihito, Hirashima Junko, Izumi Shinyu, Sugiyama Haruhito
Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Department of Respiratory Medicine, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Respir Investig. 2014 Mar;52(2):144-6. doi: 10.1016/j.resinv.2013.07.006. Epub 2013 Aug 30.
Bronchus-associated lymphoid tissue (BALT) lymphoma of the trachea, an important differential diagnosis for tracheal tumors, is a rare disease with characteristic bronchoscopic findings. In this study, we reviewed 2 cases of patients who were symptomatic at the time of diagnosis, with tumors in the trachea and left main bronchus, putting them at high risk for asphyxia. Chemotherapies including rituximab were administered, and complete remission was confirmed in both cases. Because tracheal tumors often have a pernicious course, it might be beneficial to initiate a chemotherapeutic treatment regimen instead of adopting the "wait-and-see" approach in patients with symptomatic tracheal BALT lymphoma.
气管支气管相关淋巴组织（BALT）淋巴瘤是气管肿瘤的重要鉴别诊断疾病，是一种罕见病，具有特征性的支气管镜表现。在本研究中，我们回顾了2例诊断时出现症状的患者，其气管和左主支气管有肿瘤，存在窒息的高风险。给予了包括利妥昔单抗在内的化疗，2例均确认完全缓解。由于气管肿瘤通常病程凶险，对于有症状的气管BALT淋巴瘤患者，启动化疗治疗方案而非采取“观察等待”的方法可能是有益的。
