Hongo Norio, Kiyosue Hiro, Shuto Rieko, Kamei Noritaka, Miyamoto Shinji, Tanoue Shuichi, Mori Hiromu
Department of Radiology, Oita University Faculty of Medicine, 1-1 Idaigaoka Hasama, Yufu, Oita, Japan 879-5593.
Department of Radiology, Oita University Faculty of Medicine, 1-1 Idaigaoka Hasama, Yufu, Oita, Japan 879-5593.
J Vasc Interv Radiol. 2014 May;25(5):709-16. doi: 10.1016/j.jvir.2014.01.012. Epub 2014 Mar 11.
To evaluate the feasibility and efficacy of transarterial sac embolization with a mixture of N-butyl cyanoacrylate and ethiodized oil (Lipiodol; Guerbet Japan, Tokyo, Japan) (NBCA-LPD) for type II endoleaks after endovascular aortic repair (EVAR) using a double coaxial microcatheter technique.
A retrospective review was performed of 20 consecutive cases of type II endoleaks treated by transarterial embolization using the technique from August 2010 to June 2013. The treatment indication was persistent type II endoleak over 6 months after EVAR associated with aneurysm expansion ≥ 5 mm in maximum diameter. A 1.9-F nontapered microcatheter was advanced to the aneurysmal sac through a 2.7-F microcatheter, which was coaxially introduced through a catheter. The endpoint of the procedure was intrasaccular filling with NBCA-LPD and occlusion of the feeder of the type II endoleak. The technical success rate was defined as success in transarterial intrasaccular approach followed by embolization of the intrasaccular channel and inflow arteries. Clinical success was defined as aneurysmal sac shrinkage or stabilization (freedom from sac expansion > 5 mm in maximum diameter).
Technical success was achieved in 18 of 20 cases. During a mean follow-up period of 18.5 months, complete sac occlusion was observed in 13 cases (65%). Clinical success was achieved in 16 cases (80%). No serious complications were observed.
The transarterial intrasaccular approach with a double coaxial microcatheter technique can be successfully performed in most cases, and transarterial aneurysm sac embolization using NBCA-LPD has been proven to be feasible.
使用双同轴微导管技术,评估经动脉用氰基丙烯酸正丁酯与乙碘油(Lipiodol;日本东京Guerbet Japan公司)的混合物(NBCA-LPD)栓塞治疗血管腔内主动脉修复术(EVAR)后Ⅱ型内漏的可行性和疗效。
回顾性分析2010年8月至2013年6月期间连续20例采用该技术经动脉栓塞治疗Ⅱ型内漏的病例。治疗指征为EVAR术后6个月以上持续存在的Ⅱ型内漏,且动脉瘤最大直径扩张≥5mm。将一根1.9F非锥形微导管通过一根2.7F微导管推进至动脉瘤囊内,2.7F微导管通过一根导管同轴引入。手术终点为动脉瘤囊内充满NBCA-LPD并闭塞Ⅱ型内漏的供血动脉。技术成功率定义为经动脉进入动脉瘤囊成功,随后栓塞囊内通道和流入动脉。临床成功定义为动脉瘤囊缩小或稳定(最大直径扩张>5mm的囊扩张停止)。
20例中有18例取得技术成功。在平均18.5个月的随访期内,13例(65%)观察到动脉瘤囊完全闭塞。16例(80%)取得临床成功。未观察到严重并发症。
大多数情况下,采用双同轴微导管技术经动脉进入动脉瘤囊的方法可以成功实施,并且已证明使用NBCA-LPD经动脉栓塞动脉瘤囊是可行的。