Kalantari Mojgan, Negahdari Arezou, Roknsharifi Shima, Qorbani Mostafa
Department of Radiology, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Public Health, Alborz University of Medical Sciences, Karaj, Iran. ; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Reprod Med. 2013 Nov;11(11):933-8.
Abdominal circumference (AC), biparietal diameters (BPD) and femoral length (FL) are now the main parameters used to obtain estimated fetal weight (EFW). Although the role of soft tissue parameters in determining fetal weight was proved but clinical attention to mid-thigh soft tissue thickness (STT) is limited.
To find the impression of STT on birth weight (BW) and represent a new predictive formula.
One hundred and fourteen normal singleton term (36-42w) pregnancies with delivery within 72 hours were randomly selected to participate in this prospective cohort study. Variables measured by ultrasonography before birth included: AC, BPD, FL and STT. The actual neonatal BW was also measured after birth. Linear regression model was used and R square and p-value were reported.
The mean (SD) of BW was 3406 (405) gr. R square was best fit for the model that STT was added to AC, BPD, FL (r(2): 0.77). R square for the model using BPD, AC, FL and model using BPD, STT, FL was the same (r(2): 0.7). Best fit formula was Log (BW)= 2.461+0.003BPD+0.001AC+0.007STT+0.005FL.
AC (R: 0.67, p<0.001), STT (R: 0.50, p<0.001), BPD (R: 0.59, p<0.001), FL (R: 0.66, p<0.001) were significantly correlated with birth weight. AC had also significant correlation with STT (p=0.001) CONCLUSION: This study showed adding STT to other variables in predictive models of fetal weight would provide a nice estimation (r(2)=0.77) and in cases that measuring AC is suboptimal STT may be a good replacement.
腹围（AC）、双顶径（BPD）和股骨长度（FL）现在是用于获取胎儿估计体重（EFW）的主要参数。尽管软组织参数在确定胎儿体重中的作用已得到证实，但临床对大腿中部软组织厚度（STT）的关注有限。
探讨STT对出生体重（BW）的影响，并提出一种新的预测公式。
随机选取114例单胎足月（36 - 42周）且在72小时内分娩的正常孕妇参与这项前瞻性队列研究。出生前通过超声测量的变量包括：AC、BPD、FL和STT。出生后也测量了实际的新生儿BW。使用线性回归模型，并报告决定系数（R平方）和p值。
BW的平均值（标准差）为3406（405）克。决定系数（R平方）最适合将STT添加到AC、BPD、FL的模型（r(2)：0.77）。使用BPD、AC、FL的模型和使用BPD、STT、FL的模型的决定系数（R平方）相同（r(2)：0.7）。最佳拟合公式为Log（BW）= 2.461 + 0.003BPD + 0.001AC + 0.007STT + 0.005FL。
AC（R：0.67，p < 0.001）、STT（R：0.50，p < 0.001）、BPD（R：0.59，p < 0.001）、FL（R：0.66，p < 0.001）与出生体重显著相关。AC与STT也有显著相关性（p = 0.001）。结论：本研究表明，在胎儿体重预测模型中，将STT添加到其他变量中可提供良好的估计（r(2)=0.77），并且在测量AC不理想的情况下，STT可能是一个很好的替代指标。
