Haerian-Ardakani Ahmad, Eslami Zia, Rashidi-Meibodi Fahimeh, Haerian Alireza, Dallalnejad Pantea, Shekari Marjan, Moein Taghavi Amir, Akbari Solmaz
Department of Periodontology, Faculty of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Department of Pediatric, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Iran J Reprod Med. 2013 Aug;11(8):625-30.
Periodontal infections, which serve as a reservoir of inflammatory mediators, may pose a threat to the fetal-placental unit and cause adverse pregnancy outcomes.
The aim of this study was assessing the periodontal status of women during puerperium and determining the possible relationship between their periodontal disease and low birth weight delivery.
This was a case-control study. The sample included 88 ex-pregnant women were seen at maternity hospitals of Yazd, Iran. Half of the mothers had low birth babies (LBW) (birth weight below 2500g- case group) and the others had normal weight babies (>2500g- control group). The mothers' data were obtained from medical files, interview and periodontal clinical examination carried out up to 3 days after delivery. Bleeding on probing, presence of supra-gingival calculus and CPITN (Community Periodontal Index for Treatment Needs) were used for periodontal assessment Results: Among the known risk factors of LBW babies, history of previous LBW infant among case mothers reached statistical significance (p=0.0081, Student t-test). Mothers of LBW infants had less healthy areas of gingiva (p=0.042), and more deep pockets (p=0.0006, Mann-Whitney test).
The maternal periodontal disease can be a potential independent risk factor for LBW.
牙周感染作为炎症介质的储存库,可能对胎儿 - 胎盘单位构成威胁并导致不良妊娠结局。
本研究旨在评估产褥期妇女的牙周状况,并确定其牙周疾病与低体重儿分娩之间的可能关系。
这是一项病例对照研究。样本包括在伊朗亚兹德妇产医院就诊的88名曾怀孕的妇女。一半母亲所生婴儿为低体重儿(LBW)(出生体重低于2500g - 病例组),另一半母亲所生婴儿体重正常(>2500g - 对照组)。母亲的数据来自医疗档案、访谈以及分娩后3天内进行的牙周临床检查。使用探诊出血、龈上牙石的存在情况和社区牙周治疗需求指数(CPITN)进行牙周评估。结果:在低体重儿已知的危险因素中,病例组母亲既往有低体重儿史具有统计学意义(p = 0.0081,Student t检验)。低体重儿母亲的牙龈健康区域较少(p = 0.042),深牙周袋较多(p = 0.0006,Mann - Whitney检验)。
母亲的牙周疾病可能是低体重儿的一个潜在独立危险因素。