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[爆轰合成改性纳米金刚石对人血蛋白质组分的影响]

[The effect of modified nano-diamonds of detonation synthesis on the protein fractions of human blood].

作者信息

Botvich Iu A, Olkhovskiĭ I A, Baron I I, Puzyr' A P, Baron A V, Bondar' V S

出版信息

Klin Lab Diagn. 2013 Nov(11):35-9.

PMID:24640108
Abstract

It is established that the modified nano-diamonds of detonation synthesis are able to bind serum proteins of human blood. The relative selectivity is established concerning the effect of modified nano-diamonds of detonation synthesis on beta2- and gamma-globulin fractions of serum. The evidence of concentration dependence of effect of modified nano-diamonds of detonation synthesis from serum proteins is established. The study results make it possible to consider modified nano-diamonds of detonation synthesis as a potential sorbent in technologies of hemodialysis, plasmapheresis, isolation of blood proteins and as a foundation for development of new systems of laboratory diagnostic.

摘要

已确定爆轰合成的改性纳米金刚石能够结合人血清蛋白。确定了爆轰合成的改性纳米金刚石对血清β2-球蛋白和γ-球蛋白组分作用的相对选择性。确定了爆轰合成的改性纳米金刚石对血清蛋白作用的浓度依赖性证据。研究结果使人们有可能将爆轰合成的改性纳米金刚石视为血液透析、血浆置换、血液蛋白分离技术中的潜在吸附剂,并作为开发新型实验室诊断系统的基础。

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