[侵袭性胸腺瘤伴肺转移。采用CHOP-BLEO方案手术及化疗后5年完全缓解]
[Invasive thymoma with pulmonary metastasis. Complete remission 5 years after surgery and chemotherapy using the CHOP-BLEO protocol].
作者信息
Wurtz A, Ramon P, Chambon J P, Wallaert B, Gosselin B
机构信息
Clinique chirurgicale Ouest (Chirurgie A), Hôpital Claude-Huriez, CHU, Lille.
出版信息
Rev Mal Respir. 1988;5(6):651-4.
We report a case of invasive lympho-epithelial thymoma with pulmonary metastases, treated by complete macroscopic excision of primary tumour and then by chemotherapy using CHOP-BLEO. The epithelial nature of the tumour was confirmed by immunohistochemical studies. Chemotherapy enabled a complete and prolonged remission (greater than 63 months). Therapeutic trials of CHOP-BLEO merit further assessment and the results should be compared to the baseline treatment using platinum and prednisolone.
我们报告一例伴有肺转移的侵袭性淋巴上皮性胸腺瘤，通过对原发肿瘤进行完整的肉眼切除，然后使用CHOP-BLEO方案进行化疗。免疫组织化学研究证实了肿瘤的上皮性质。化疗实现了完全且持久的缓解（超过63个月）。CHOP-BLEO方案的治疗试验值得进一步评估，其结果应与使用铂类和泼尼松龙的基线治疗进行比较。
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