Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center, 800 Washington Street #178, Proger 7, Boston, MA 02111, USA.
Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center, 800 Washington Street #178, Proger 7, Boston, MA 02111, USA.
J Clin Neurosci. 2014 Jul;21(7):1141-7. doi: 10.1016/j.jocn.2013.11.007. Epub 2013 Dec 8.
Although advances in endovascular techniques have permitted reconstruction of intimal dissections and related pseudoaneurysms of the extracranial cervical internal carotid artery, highly tortuous tonsillar loop anatomic variants still pose an obstacle to conventional extracranial self-expanding carotid stents. During a 12 year period, nine of 48 cases with cervical carotid dissections were associated with a tonsillar loop. Five patients required endovascular treatment, which was performed using a microcatheter-based technique with the low-profile Enterprise vascular reconstruction device (Codman Neurovascular, Raynham, MA, USA). Technical, radiographic, and clinical outcomes were analyzed for each patient. Dissection etiology was spontaneous in three patients, iatrogenic in one, and traumatic in one. Four near-occlusive tonsillar loop dissections were successfully recanalized during the acute phase. Dissection-related stenosis improved from 90±22% to 31±13%, with tandem stents needed in three instances to seal the inflow zone. There were no procedure-related transient ischemic attacks (TIA), minor/major strokes, or deaths. Angiographic follow-up for a mean of 28.0±21.6 months showed all stents were patent, with average stenosis of 25.2±12.2%. Focal ovalization and kinking of the closed-cell design was noted at the sharpest curve in one patient. Clinical outcome (follow-up of 28.1±21.5 months) demonstrated overall improvement with no clinical worsening, new TIA, or stroke. Tonsillar loop-associated carotid dissections can be successfully and durably recanalized using the low-profile Enterprise stent with an excellent long-term patency rate and low procedural risk. The possibility of stent kinking and low radial force should be considered when planning reconstruction with this device.
尽管血管内技术的进步使得颅外颈内动脉内膜夹层和相关假性动脉瘤的重建成为可能,但高度扭曲的扁桃体环解剖变异仍然是传统颅外自膨式颈动脉支架的障碍。在 12 年期间,48 例颈内动脉夹层中有 9 例与扁桃体环有关。5 例患者需要血管内治疗,采用基于微导管的技术和低轮廓 Enterprise 血管重建装置(Codman Neurovascular,雷纳姆,MA,美国)进行治疗。分析了每位患者的技术、影像学和临床结果。3 例患者的夹层病因是自发性的,1 例是医源性的,1 例是创伤性的。在急性期成功地再通了 4 例近乎闭塞的扁桃体环夹层。与夹层相关的狭窄从 90±22%改善到 31±13%,在 3 例情况下需要串联支架来封闭流入区。没有与手术相关的短暂性脑缺血发作(TIA)、小/大卒中和死亡。平均 28.0±21.6 个月的血管造影随访显示所有支架均通畅,平均狭窄率为 25.2±12.2%。在一名患者中,在最陡峭的曲线处观察到封闭细胞设计的局部椭圆形和扭结。临床结果(28.1±21.5 个月的随访)显示整体改善,无临床恶化、新 TIA 或中风。使用低轮廓 Enterprise 支架可以成功且持久地再通与扁桃体环相关的颈动脉夹层,具有极好的长期通畅率和低手术风险。在使用该装置进行重建时,应考虑支架扭结和低径向力的可能性。