急性淋巴细胞白血病中的苏丹黑B阳性

Sudan black B positivity in acute lymphoblastic leukemia.

作者信息

Charak B S, Advani S H, Karandikar S M, Parikh P M, Nair C N, Das Gupta A, Gopal R, Tapan K S, Nadkarni K S, Kurkure P A

机构信息

Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.

出版信息

Acta Haematol. 1988;80(4):199-202. doi: 10.1159/000205637.

DOI:10.1159/000205637

PMID:2464265

Abstract

The records of 458 patients with acute lymphoblastic leukemia (ALL) have been reviewed. The diagnosis of ALL was based on clinical examination and morphological, cytochemical and immunophenotypic characteristics (20% or more blasts reacting with lymphoid monoclonal antibodies) of blood and/or bone marrow. Blast cells of 6 (1.3%) patients showed positive reaction with Sudan black B (SBB) in the absence of reactivity to any other myeloid markers. Positive reaction with SBB stain cannot be considered specific for myeloid series.

摘要

对458例急性淋巴细胞白血病（ALL）患者的记录进行了回顾。ALL的诊断基于临床检查以及血液和/或骨髓的形态学、细胞化学和免疫表型特征（20%或更多的原始细胞与淋巴系单克隆抗体反应）。6例（1.3%）患者的原始细胞在对任何其他髓系标志物无反应的情况下，对苏丹黑B（SBB）呈阳性反应。SBB染色呈阳性反应不能被认为是髓系特异性的。