与局部应用加替沙星相关的角膜晶体沉积物。
Corneal crystalline deposits associated with topically applied gatifloxacin.
机构信息
Department of Ophthalmology and Visual Science, Yale Eye Center, Yale University School of Medicine, New Haven, CT.
出版信息
Cornea. 2014 Jun;33(6):638-9. doi: 10.1097/ICO.0000000000000101.
PURPOSE
To report a case of corneal crystalline deposits from the use of gatifloxacin 0.5% topical antibiotic after combined cataract extraction and trabeculotomy ab interno surgery.
METHODS
A 59-year-old woman presented after combined cataract extraction and trabeculotomy ab interno with crystalline deposits in the anterior corneal stroma. Clinical examination and slit-lamp photography were performed.
RESULTS
The slit-lamp examination showed inferior white crystal deposition in the anterior stroma with overlying punctate epithelial erosions 4 weeks postoperatively. The eye was asymptomatic, but the deposition was cosmetically noticeable to the patient. Serial slit-lamp photography demonstrated resolution of the crystalline deposits 30 days after the discontinuation of eye drops.
CONCLUSIONS
The authors present a rare case of stromal crystallization from topical gatifloxacin treatment. Complete resolution of corneal deposits was seen 30 days after the discontinuation of the drops without sequelae.
目的
报告一例在白内障超声乳化吸出术联合内路小梁切开术后使用加替沙星 0.5%眼用抗生素引起的角膜晶体状沉积物。
方法
一位 59 岁女性，在白内障超声乳化吸出术联合内路小梁切开术后 4 周，出现前角膜基质内的晶体状沉积物，进行了临床检查和裂隙灯照相。
结果
裂隙灯检查显示下侧白色晶体状沉积物在前基质中，伴有上皮点状糜烂。眼部无症状，但沉积对患者有美容影响。连续的裂隙灯照相显示，在停药 30 天后，晶体沉积物得到解决。
结论
作者报告了一例罕见的局部应用加替沙星引起的基质结晶。停药 30 天后，角膜沉积物完全消退，无后遗症。
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