Alshamrani Abdulaziz A, Alharbi Saad S
King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Saudi J Ophthalmol. 2019 Apr-Jun;33(2):163-164. doi: 10.1016/j.sjopt.2018.04.006. Epub 2018 Apr 26.
Corneal deposits have been reported with numerous topical medications including fluoroquinolones. However, they have not been documented as a side effect of topical moxifloxacin. In this report, we describe the first case of corneal deposits following the use of preservative-free topical moxifloxacin 0.5% eye drops in a 26-year-old male with keratoconus who underwent a unilateral corneal cross-linking. Increased frequency and prolonged instillation of moxifloxacin eye drops led to corneal precipitation in this patient. Complete resolution of corneal deposits occurred four months after drug discontinuation without sequelae.
角膜沉积物已在包括氟喹诺酮类在内的多种局部用药中被报道。然而，它们尚未被记录为局部使用莫西沙星的副作用。在本报告中，我们描述了首例在一名26岁患有圆锥角膜且接受了单侧角膜交联手术的男性患者中，使用不含防腐剂的0.5%局部用莫西沙星滴眼液后出现角膜沉积物的病例。莫西沙星滴眼液使用频率增加和滴注时间延长导致该患者出现角膜沉淀。停药四个月后角膜沉积物完全消退，且无后遗症。
