Ip Eric J, Trinh Karen, Tenerowicz Michael J, Pal Jai, Lindfelt Tristan A, Perry Paul J
Department of Pharmacy Practice, Touro University California College of Pharmacy, Vallejo, CA, USA
Department of Pharmacy Practice, Touro University California College of Pharmacy, Vallejo, CA, USA.
J Pharm Pract. 2015 Oct;28(5):450-6. doi: 10.1177/0897190014527319. Epub 2014 Mar 18.
To compare and contrast the characteristics of 2 groups of men ≥40 years old: reported anabolic-androgenic steroid (AAS) users and nonusers.
Cross-sectional survey.
Thirty-eight online fitness, weight lifting, bodybuilding, and steroid Web sites.
A total of 67 male AAS users and 76 male nonusers ≥40 years old.
Demographics, utilization of AAS and other performance-enhancing agents (PEAs), exercise patterns, history of illicit drugs and alcohol use, and psychiatric traits/diagnoses.
The majority of AAS users ≥40 years old were caucasian (92.5%), heterosexual (97.0%), and classified themselves as recreational exercisers (79.1%). AAS users took more PEAs (11.5 ± 5.6 vs 4.6 ± 2.7; P < .001), were more likely to binge drink (47.8% vs 29.0%; P = .025), report heavy alcohol use (21.0% vs 7.9%; P = .031), meet criteria for substance dependence disorder (27.4% vs 4.0%; P < .001), and report an anxiety disorder diagnosis (12.0% vs 2.6%; P = .046) than nonusers.
AAS misuse is prevalent among older men and is associated with polypharmacy, more aggressive alcohol use, and a higher incidence of substance dependence and anxiety disorders compared to nonusers. This information may help clinicians and researchers identify and develop appropriate intervention strategies for AAS abuse among older men.
比较和对比两组40岁及以上男性的特征：报告使用合成代谢雄激素类固醇（AAS）者和未使用者。
横断面调查。
38个在线健身、举重、健美和类固醇网站。
共有67名40岁及以上的男性AAS使用者和76名男性未使用者。
人口统计学特征、AAS和其他增强运动表现药物（PEA）的使用情况、运动模式、非法药物和酒精使用史以及精神特质/诊断。
40岁及以上的AAS使用者大多数为白种人（92.5%）、异性恋（97.0%），并将自己归类为休闲锻炼者（79.1%）。与未使用者相比，AAS使用者服用更多的PEA（11.5±5.6对4.6±2.7；P<.001），更可能狂饮（47.8%对29.0%；P=.025）、报告大量饮酒（21.0%对7.9%；P=.031）、符合物质依赖障碍标准（27.4%对4.0%；P<.001）以及报告有焦虑症诊断（12.0%对2.6%；P=.046）。
AAS滥用在老年男性中很普遍，与多药合用、更激进的酒精使用以及与未使用者相比更高的物质依赖和焦虑症发病率相关。这些信息可能有助于临床医生和研究人员识别并制定针对老年男性AAS滥用的适当干预策略。
