脑脊液中氨基糖苷类生物测定的血清标准品。
Serum standards for the bioassay of aminoglycosides in cerebrospinal fluid.
作者信息
Hammerberg S, Sinai R, Marks M I
出版信息
J Clin Pathol. 1978 Feb;31(2):172-4. doi: 10.1136/jcp.31.2.172.
Abstract
Four diluents were compared as reference standards for the assay of gentamicin in cerebrospinal fluid (CSF): human CSF, human serum, distilled water, and 150 mmol NaCl/4.5 mmol CaCl2. Standards prepared in pooled human serum were the best alternative to CSF for the assay of gentamicin and were also useful for the assay of tobramycin, netilmicin, amikacin, and sisomicin. The pH (6.0-9.8) of CSF did not alter the results of the assay.
摘要
比较了四种稀释剂作为脑脊液（CSF）中庆大霉素测定的参考标准：人脑脊液、人血清、蒸馏水和150 mmol氯化钠/4.5 mmol氯化钙。用人混合血清制备的标准品是庆大霉素测定中脑脊液的最佳替代物，也可用于妥布霉素、奈替米星、阿米卡星和西索米星的测定。脑脊液的pH值（6.0 - 9.8）不会改变测定结果。
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LABORATORY STUDIES ON GENTAMICIN.庆大霉素的实验室研究
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Simplified, accurate method for antibiotic assay of clinical specimens.临床标本抗生素检测的简化、准确方法。
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The rate of bacteriologic response to antimicrobial therapy in neonatal meningitis.新生儿脑膜炎对抗菌治疗的细菌学反应率。
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Assay of gentamicin in cerebrospinal fluid.脑脊液中庆大霉素的测定。
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A controlled study of intrathecal antibiotic therapy in gram-negative enteric meningitis of infancy. Report of the neonatal meningitis cooperative study group.
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Factors affecting plate assay of gentamicin I diluents.
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