Rapini R P, Golitz L E
Department of Dermatology, University of Texas Medical School, Houston 77030.
J Am Acad Dermatol. 1989 Feb;20(2 Pt 1):266-71. doi: 10.1016/s0190-9622(89)70033-5.
Eleven cases of a peculiar, hyalinized, hypocellular dermal fibroma are reported. The lesions are characterized by epidermal atrophy, a whorled appearance of sclerotic collagen bundles separated by clefts containing mucin, and sharp demarcation of the lesions from the surrounding normal skin. They are small white or flesh-colored waxy papules. Multiple lesions of this type have been reported in the multiple hamartoma syndrome (Cowden's disease). We believe that the solitary lesions of these eleven patients who did not have Cowden's disease represent an unrecognized form of the same fibrous hamartoma that occurs in Cowden's disease.
报告了11例特殊的、玻璃样变的、细胞稀少的皮肤纤维瘤。这些病变的特征为表皮萎缩、由含黏液的裂隙分隔的硬化胶原束呈涡状外观,以及病变与周围正常皮肤界限清晰。它们为白色或肉色的小蜡样丘疹。在多发性错构瘤综合征(考登病)中曾有此类多发病变的报道。我们认为这11例无考登病的患者的孤立性病变代表了考登病中出现的同一纤维性错构瘤的一种未被认识的形式。