Yang Hai-Tao, Tang Weiming, Xiao Zhan-Pei, Jiang Ning, Mahapatra Tanmay, Huan Xi-Ping, Yin Yue-Ping, Wang Xiao-Liang, Chen Xiang-Sheng, Fu Geng-Feng
Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu, China.
Department of Epidemiology, School of Public Health, University of California, Los Angeles.
Clin Infect Dis. 2014 Jun;58(12):1753-9. doi: 10.1093/cid/ciu175. Epub 2014 Mar 18.
Epidemics of human immunodeficiency virus (HIV) and syphilis among men who have sex with men (MSM) are major public health concerns in most parts of China. A dearth of information regarding the current trend of HIV in this hard-to-reach population in several regions including Jiangsu, coupled with the reemergence of syphilis, calls for an effort to understand the dynamics of the dual epidemic in this province.
To estimate the occurrence and burden of these 2 sexually transmitted diseases and the distribution of their potential sociobehavioral correlates among MSM in Jiangsu, 2 cohort studies were conducted in Yangzhou and Changzhou cities.
Among 839 participants, 48% were married, 51.7% had sex with women in the last 6 months, and 25.5% did not use condoms during their last anal intercourse. The observed incidence of HIV was 13.59 and 12.62 and that of syphilis was 7.33 and 13.25 per 100 person-years among the participants of Yangzhou and Changzhou, respectively. The baseline prevalence of HIV and syphilis was 16.0% and 29.9% in Yangzhou and 13.6% and 14.9% in Changzhou, respectively.
Considerably high incidence and prevalence of HIV and syphilis among participants and their potential bridging role in transmitting these infections to the general population in Yangzhou and Changzhou cities calls for urgent effective intervention strategies.
在中国大部分地区，男男性行为者（MSM）中人类免疫缺陷病毒（HIV）和梅毒的流行是主要的公共卫生问题。包括江苏在内的几个地区，关于这一难以接触人群中HIV当前趋势的信息匮乏，再加上梅毒的再度出现，需要努力了解该省双重疫情的动态。
为了估计这两种性传播疾病的发生率和负担以及它们在江苏MSM中潜在的社会行为相关因素的分布，在扬州市和常州市进行了两项队列研究。
在839名参与者中，48%已婚，51.7%在过去6个月内与女性发生过性行为，25.5%在最后一次肛交时未使用避孕套。在扬州和常州的参与者中，观察到的HIV发病率分别为每100人年13.59和12.62，梅毒发病率分别为每100人年7.33和13.25。扬州HIV和梅毒的基线患病率分别为16.0%和29.9%，常州分别为13.6%和14.9%。
扬州和常州市参与者中HIV和梅毒的发病率和患病率相当高，以及他们在将这些感染传播给普通人群中可能起到的桥梁作用，需要采取紧急有效的干预策略。
