Fu Geng-Feng, Jiang Ning, Hu Hai-Yang, Mahapatra Tanmay, Yin Yue-Ping, Mahapatra Sanchita, Wang Xiao-Liang, Chen Xiang-Sheng, Babu Giridhar R, Xu Xiao-Qin, Ding Ping, Qiu Tao, Liu Xiao-Yan, Guo Hongxiong, Huan Xi-Ping, Tang Weiming
Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing, China.
PLoS One. 2015 Mar 16;10(3):e0118863. doi: 10.1371/journal.pone.0118863. eCollection 2015.
In China, the HIV/AIDS epidemic is expanding among men who have sex with men (MSM). As independent risk factors of HIV infection, the epidemics of Chlamydia (CT) and Gonorrhea (NG) in MSM were not well studied, particular for the risk factors of these infectious. The objectives of current reported study were to understand the dynamics of HIV and other sexual transmitted infections (STIs) among MSM in Jiangsu, China, and to measure factors that correlated with STIs.
In order to gain more participants, a multisite cross-sectional study design was used in our study, by using convenience-sampling to recruit MSM in two Changzhou and Yangzhou, Jiangsu, China, between the July and October of 2009.
In this comprehensive survey involving MSM in two cities of Jiangsu province of China, the prevalence of STIs of CT (6.54%), NG (3.63%), syphilis (20.34%) and HIV (11.62%) were measured. Overall, the STIs prevalence (CT, NG or syphilis) for the participants in our study was 26.39%, meanwhile, 3.4% (14 out of the 413) participants had at least two kinds of STIs. Meeting casual partners at parks, public restrooms or other public areas, having had anal sex with men in the past six months, having had STI symptoms in the past year were positively correlated with STIs positive, with adjusted ORs of 4.61(95%CI 1.03-20.75), 1.91(95%CI 1.14-3.21) and 2.36(95%CI 1.07,5.24).
Our study findings reiterate the fact that Chinese MSM are highly susceptible to acquiring syphilis, CT, NG and HIV, and there is an urgent need for intervention targeted towards this population. Behavioral measures should constitute an important part of the targeted intervention. Furthermore, the already implemented preventive and diagnostic services for HIV should be expanded to include syphilis CT and NG, too.
在中国，男男性行为者（MSM）中的艾滋病毒/艾滋病疫情正在蔓延。作为艾滋病毒感染的独立危险因素，MSM中衣原体（CT）和淋病（NG）的流行情况尚未得到充分研究，尤其是这些感染的危险因素。本报告研究的目的是了解中国江苏省MSM中艾滋病毒和其他性传播感染（STIs）的动态情况，并衡量与性传播感染相关的因素。
为了招募更多参与者，我们的研究采用了多地点横断面研究设计，于2009年7月至10月在中国江苏省常州和扬州两地通过便利抽样招募MSM。
在这项涉及中国江苏省两个城市MSM的综合调查中，测量了CT（6.54%）、NG（3.63%）、梅毒（20.34%）和艾滋病毒（11.62%）的性传播感染患病率。总体而言，我们研究参与者的性传播感染（CT、NG或梅毒）患病率为26.39%，同时，3.4%（413名参与者中的14名）至少患有两种性传播感染。在公园、公共厕所或其他公共场所结识临时伴侣、在过去六个月内与男性发生肛交、在过去一年有性传播感染症状与性传播感染呈阳性呈正相关，调整后的比值比分别为4.61（95%置信区间1.03 - 20.75）、1.91（95%置信区间1.14 - 3.21）和2.36（95%置信区间1.07,5.24）。
我们的研究结果重申了一个事实，即中国MSM极易感染梅毒、CT、NG和艾滋病毒，迫切需要针对这一人群进行干预。行为措施应成为针对性干预的重要组成部分。此外，已经实施的艾滋病毒预防和诊断服务也应扩大到包括梅毒、CT和NG。
