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一项大型队列研究中的孕期职业性提举与儿童出生体重

Occupational lifting during pregnancy and child's birth size in a large cohort study.

作者信息

Juhl Mette, Larsen Pernille Stemann, Andersen Per Kragh, Svendsen Susanne Wulff, Bonde Jens Peter, Nybo Andersen Anne-Marie, Strandberg-Larsen Katrine

机构信息

The Research Unit Women's and Children's Health, The Juliane Marie Centre, Rigshospitalet, Dep.7821, DK - 2100 Copenhagen Ø, Denmark.

出版信息

Scand J Work Environ Health. 2014 Jul;40(4):411-9. doi: 10.5271/sjweh.3422. Epub 2014 Mar 19.

Abstract

OBJECTIVES

It has been suggested that the handling of heavy loads during pregnancy is associated with impaired fetal growth. We examined the association between quantity and frequency of maternal occupational lifting and the child's size at birth, measured by weight, length, ponderal index, small-for-gestational-age (SGA), abdominal circumference, head circumference, and placental weight.

METHODS

We analyzed birth size from the Danish Medical Birth Registry of 66 693 live-born children in the Danish National Birth Cohort according to the mother's self-reported information on occupational lifting from telephone interviews around gestational week 16. Data were collected in the period 1996-2002. We used linear and logistic regression models and adjusted for confounders.

RESULTS

In the fully adjusted models, most of the mean differences in birth size measures had values indicating a smaller size of offspring among women with occupational lifting versus women with no lifting, but the differences were very small, and there was a statistically significant trend only for placental weight showing lighter weight with increasing number of kilos lifted per day. In jobs likely to include person-lifting, we found increased odds of SGA among children of women who lifted 501-1000 kilos per day [odds ratio (OR) 1.34, 95% confidence interval (95% CI) 0.98-1.83] and >1000 kilos per day (OR 1.51, 95% CI 0.83-2.76) compared to no lifting. In jobs with no person-lifting, occupational lifting was not associated with SGA.

CONCLUSIONS

Overall, we observed no strong support for an association between maternal occupational lifting and impaired size at birth. Our data indicated a potential association between lifting and SGA among offspring of women in occupations that are likely to include person-lifting. These results should, however, be interpreted with caution due to limited statistical power, and we suggest that future studies include detailed, individual information on job functions and ergonomic routines of lifting procedures.

摘要

目的

有人提出孕期搬运重物与胎儿生长受限有关。我们研究了母亲职业性提举的数量和频率与孩子出生时的大小之间的关联,出生时的大小通过体重、身长、体重指数、小于胎龄儿(SGA)、腹围、头围和胎盘重量来衡量。

方法

根据母亲在妊娠第16周左右通过电话访谈自我报告的职业提举信息,我们分析了丹麦国家出生队列中66693名活产儿童的丹麦医学出生登记处的出生大小数据。数据收集于1996年至2002年期间。我们使用线性和逻辑回归模型,并对混杂因素进行了调整。

结果

在完全调整的模型中,大多数出生大小测量指标的平均差异值表明,从事职业提举的女性所生后代的体型小于未从事提举的女性,但差异非常小,仅胎盘重量有统计学意义的趋势,即每天提举的公斤数增加,胎盘重量更轻。在可能包括搬运人的工作中,我们发现,与不搬运的女性相比,每天搬运501 - 1000公斤[比值比(OR)1.34,95%置信区间(95%CI)0.98 - 1.83]和每天搬运超过1000公斤(OR 1.51,95%CI 0.83 - 2.76)的女性所生子女中SGA的几率增加。在不涉及搬运人的工作中,职业提举与SGA无关。

结论

总体而言,我们没有观察到有力证据支持母亲职业提举与出生时体型受损之间存在关联。我们的数据表明,在可能包括搬运人的职业中,女性提举与后代SGA之间可能存在关联。然而,由于统计效力有限,这些结果应谨慎解释,我们建议未来的研究纳入关于工作职能以及提举程序的人体工程学常规的详细个体信息。

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