Department of Ophthalmology, Philipps University of Marburg, Baldinger Strasse, Marburg, 35043, Germany,
Graefes Arch Clin Exp Ophthalmol. 2014 May;252(5):837-43. doi: 10.1007/s00417-014-2608-4. Epub 2014 Mar 20.
To report one year results of the first cohort of routine refractive lenticule extraction through a small incision (ReLEx SMILE) for correction of myopia and myopic astigmatism.
Fifty-four eyes of 27 patients with spherical equivalent of -4.68 ± 1.29D who underwent routine ReLEx SMILE by a single surgeon were prospectively followed-up for 1 year. We used the VisuMax femtosecond laser system (Carl Zeiss Meditec AG, Germany) with a 500 kHz repetition rate. Folow-up intervals were at 1 day, 1 week, 1, 3, 6, and 12 months after surgery. We obtained following parameters: uncorrected (UDVA) and distance-corrected visual acuity (CDVA), contrast sensitivity, and wave front measurements. We also recorded all complications.
Because of suction loss in one eye, 12-month results were obtained in 53 eyes as follows. After 1 year, 88% of eyes with plano target had an UDVA of 20/20 or better. Twelve percent of eyes lost 1 line of CDVA, while 31% gained 1 line and 3% gained 2 lines. The mean SE after 1 year was -0.19 ± 0.19. The mean refraction change between month 1 and 12 was 0.08 D. Neither mesopic nor photopic contrast sensitivity showed any significant changes. The high-order aberrations (HOA) increased from 0.17 to 0.27 μm (Malacara notation). No visually threatening complications were observed.
In this first cohort, ReLEx SMILE produced satisfactory refractive outcomes with moderate induction of HOA and unaffected contrast sensitivity after 1 year.
报告首例通过小切口（ReLEx SMILE）常规进行的屈光性透镜切除术治疗近视和近视散光的一年结果。
前瞻性随访 27 名患者（54 只眼），手术均由同一位医生完成，平均等效球镜度为-4.68 ± 1.29D。使用 500 kHz 重复率的 VisuMax 飞秒激光系统（德国卡尔蔡司公司）。术后随访时间为 1 天、1 周、1、3、6 和 12 个月。我们获得了以下参数：未矫正（UDVA）和距离校正视力（CDVA）、对比敏感度和波前测量值。同时记录所有并发症。
由于 1 只眼吸力丧失，我们获得了 53 只眼的 12 个月结果。1 年后，88%的平光目标眼的 UDVA 达到 20/20 或更好。12%的眼失去 1 行 CDVA，而 31%的眼增加 1 行，3%的眼增加 2 行。术后 1 年平均等效球镜度为-0.19 ± 0.19。第 1 个月至第 12 个月的平均屈光度变化为 0.08 D。中值和高值对比敏感度均无显著变化。高阶像差（HOA）从 0.17 增加到 0.27 μm（马拉卡纳符号）。未观察到有威胁视力的并发症。
在这个首例队列中，ReLEx SMILE 术后 1 年产生了令人满意的屈光结果，中高度像差（HOA）适度增加，对比敏感度不受影响。
