Department of Ophthalmology, Helios Hospital Erfurt, Nordhäusser Str. 74, 99089, Erfurt, Germany.
Graefes Arch Clin Exp Ophthalmol. 2010 Jul;248(7):1019-27. doi: 10.1007/s00417-009-1293-1. Epub 2010 Feb 4.
To report the 6-month results of a new method of refractive correction, femtosecond lenticule extraction (FLEx), and the preliminary outcomes in the first 108 eyes.
In this prospective study, a flap and a lenticule of intrastromal corneal tissue were cut simultaneously using a femtosecond laser. Thereafter, the lenticule was removed manually and the flap repositioned. One hundred and seven of 108 myopic eyes of 56 patients in the treatment group completed the final 6 months of follow-up. The patients' mean age was 35 years. The preoperative mean spherical equivalent (SE) was -4.59 +/- 1.3 diopters (D). The uncorrected visual acuity and the best spectacle-corrected visual acuity after 6 months, objective and manifest refractions, results of slit-lamp examination, the side effects, and the responses to a questionnaire are reported.
Six months postoperatively, the mean SE was -0.19 +/- 0.47 D; 98.1% of treated eyes were within +/-1.0 D, and 74.8% of eyes within +/-0.5 D of the intended correction. Eight (7.4%) of 108 eyes lost one line of Snellen VA, one (0.9%) eye lost two Snellen lines, 46 eyes (43%) gained one line, ten eyes (9.3%) gained two Snellen lines, and the VA remained unchanged in 42 (39.3%) eyes. The patient responses to a standardized questionnaire indicated that 97.1% of patients were satisfied with the obtained results and would undergo the procedure again.
FLEx appears to be a safe and promising corneal refractive procedure for correcting myopia.
报告一种新的屈光矫正方法——飞秒激光透镜切除术（FLEx）的 6 个月结果，并初步报告前 108 只眼的结果。
在这项前瞻性研究中，使用飞秒激光同时切割角膜基质中的瓣和透镜。然后手动切除透镜并重新定位瓣。在治疗组的 108 只近视眼中，有 107 只完成了最后 6 个月的随访。患者的平均年龄为 35 岁。术前平均等效球镜（SE）为-4.59 +/- 1.3 屈光度（D）。报告了术后 6 个月的未矫正视力和最佳矫正视力、客观和显性屈光、裂隙灯检查结果、副作用以及对问卷的反应。
术后 6 个月，平均 SE 为-0.19 +/- 0.47 D；98.1%的治疗眼在 +/-1.0 D 以内，74.8%的眼在 +/-0.5 D 以内。108 只眼中有 8 只（7.4%）视力下降一行，1 只（0.9%）视力下降两行，46 只（43%）视力提高一行，10 只（9.3%）视力提高两行，42 只（39.3%）视力不变。对标准化问卷的患者反应表明，97.1%的患者对获得的结果满意，并愿意再次接受该手术。
FLEx 似乎是一种安全且有前途的角膜屈光手术，可用于矫正近视。
