Solomatin Eye Clinic, Riga, Latvia.
Graefes Arch Clin Exp Ophthalmol. 2013 May;251(5):1437-42. doi: 10.1007/s00417-012-2220-4. Epub 2012 Dec 5.
To compare 1-year results of the refractive lenticule extraction (ReLEx) flex technique performed as a commercial bilateral simultaneous procedure to a matched group of wavefront-optimized Femto-Lasik for correction of myopia and astigmatism with emphasis on contrast sensitivity and high-order aberrations (HOA).
In this retrospective study 44 eyes of 22 patients with spherical equivalent (SE) of -5.13 D who underwent ReLEx were matched to 50 eyes of 25 patients with SE of -5.42 D treated by wavefront-optimized Femto-Lasik. We used Carl Zeiss Meditec (CZM) VisuMax(®) femtosecond laser system with a 200 kHz repetition rate. In addition, for Femto-LASIK, MEL 80 Excimer Laser (CZM) with aspheric ablation profiles was used for ablation.
At 1 year, the mean SE in the ReLEx group was -0.23 ± 0.35 D and in the Femto-LASIK group -0.15 ± 0.27 D. The mesopic contrast sensitivity of ReLEx treated eyes at 12 and 18 cpd improved from 1.49 and 0.99 to 1.54 and 1.1 respectively. In the Femto-LASIK group the numbers were pre-op 1.51 and 1.03, and after 1 year 1.54 and 1.06. The high-order aberrations (HOA) after ReLEx changed from 0.15 to 0.23 μm, and after Femto-LASIK from 0.175 to 0.320 μm (p = 0.0023).
At 1 year, wavefront-optimized Femto-LASIK produced similar refractive outcomes to ReLEx(®) flex with better, but non-significant accuracy. In contrast, ReLEx(®) flex showed significantly less induction of HOA and better mesopic mid-term contrast sensitivity then the wavefront-optimized Femto-LASIK.
比较矫正近视和散光的折射性晶状体切除术（ReLEx）flex 技术与经波前优化的 Femto-Lasik 的 1 年疗效，重点比较对比敏感度和高阶像差（HOA）。
在这项回顾性研究中，44 只眼（22 例患者）接受 ReLEx 手术，等效球镜（SE）为-5.13 D，与 SE 为-5.42 D 的 50 只眼（25 例患者）行波前优化的 Femto-Lasik 治疗相匹配。我们使用 Carl Zeiss Meditec（CZM）VisuMax（®）飞秒激光系统，重复频率为 200 kHz。此外，对于 Femto-LASIK，采用具有非球面消融曲线的 MEL 80 准分子激光（CZM）进行消融。
术后 1 年，ReLEx 组的平均 SE 为-0.23±0.35 D，Femto-LASIK 组为-0.15±0.27 D。ReLEx 治疗眼在 12 和 18 cpd 时的明视对比敏感度从术前的 1.49 和 0.99 提高到术后的 1.54 和 1.1。在 Femto-LASIK 组中，术前分别为 1.51 和 1.03，术后 1 年分别为 1.54 和 1.06。ReLEx 术后的高阶像差（HOA）从 0.15 变为 0.23μm，Femto-LASIK 术后从 0.175 变为 0.320μm（p=0.0023）。
术后 1 年，波前优化的 Femto-LASIK 与 ReLEx（®）flex 的屈光结果相似，但准确性更好，但无统计学意义。相比之下，ReLEx（®）flex 术后诱导的 HOA 明显较少，明视中期对比敏感度也明显较好。
