Rauf Sakandar, Shiddiky Muhammad J A, Trau Matt
Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Corner of College and Coopers Roads, Brisbane, QLD 4072, Australia.
Chem Commun (Camb). 2014 May 14;50(37):4813-5. doi: 10.1039/c4cc01357c.
This communication reports the use of an electrohydrodynamic surface shear force to selectively manipulate colloid-surface interactions. We demonstrate the selection of strongly (specifically) bound biomolecule-functionalized colloidal beads over more weakly (non-specifically) bound beads using a tuneable alternating current electrohydrodynamic (ac-EHD) force, which drives lateral fluid motion within a few nanometers of an electrode surface. By externally "tuning" the strength of the ac-EHD force, we demonstrate a significant enhancement of capture efficiency for specifically bound colloids, along with a removal of the adsorption of non-specific colloidal beads - a process which may be observed in real-time.
本通讯报道了利用电流体动力学表面剪切力来选择性地操控胶体与表面的相互作用。我们展示了使用可调交变电流体动力学（ac-EHD）力，从结合较弱（非特异性）的珠子中选择出结合较强（特异性）的生物分子功能化胶体珠子，该力可驱动电极表面几纳米范围内的横向流体运动。通过外部“调节”ac-EHD力的强度，我们证明了特异性结合胶体的捕获效率显著提高，同时非特异性胶体珠子的吸附被去除——这一过程可以实时观察到。
