Ramos Ercy Mara Cipulo, de Toledo-Arruda Alessandra Choqueta, Fosco Luciana Cristina, Bonfim Rafaela, Bertolini Giovana Navarro, Guarnier Flavia Alessandra, Cecchini Rubens, Pastre Carlos Marcelo, Langer Daniel, Gosselink Rik, Ramos Dionei
Department of Physiotherapy, State University of Sao Paulo, Presidente Prudente, Brazil
Department of Physiotherapy, State University of Sao Paulo, Presidente Prudente, Brazil Department of Clinical Medicine, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Clin Rehabil. 2014 Nov;28(11):1096-106. doi: 10.1177/0269215514527842. Epub 2014 Mar 19.
To investigate the effects of elastic tubing training compared with conventional resistance training on the improvement of functional exercise capacity, muscle strength, fat-free mass, and systemic inflammation in patients with chronic obstructive pulmonary disease.
A prospective, randomized, eight-week clinical trial.
The study was conducted in a university-based, outpatient, physical therapy clinic.
A total of 49 patients with moderate chronic obstructive pulmonary disease.
Participants were randomly assigned to perform elastic tubing training or conventional resistance training three times per week for eight weeks.
The primary outcome measure was functional exercise capacity. The secondary outcome measures were peripheral muscle strength, health-related quality of life assessed by the Chronic Respiratory Disease Questionnaire (CRDQ), fat-free mass, and cytokine profile.
After eight weeks, the mean distance covered during six minutes increased by 73 meters (±69) in the elastic tubing group and by 42 meters (±59) in the conventional group (p < 0.05). The muscle strength and quality of life improved in both groups (P < 0.05), with no significant differences between the groups. There was a trend toward an improved fat-free mass in both groups (P = 0.05). After the first and last sessions, there was an increase in interleukin 1β (IL-1β) and interleukin 10 (IL-10) in both groups, while tumour necrosis factor alpha (TNF-α) was stimulated only in the conventional training group.
Elastic tubing training had a greater effect on functional exercise capacity than conventional resistance training. Both interventions were equally effective in improving muscle strength and quality of life.
探讨弹力管训练与传统阻力训练相比，对改善慢性阻塞性肺疾病患者的功能运动能力、肌肉力量、去脂体重和全身炎症的影响。
一项前瞻性、随机、为期八周的临床试验。
该研究在一所大学附属的门诊物理治疗诊所进行。
共49例中度慢性阻塞性肺疾病患者。
参与者被随机分配，每周进行三次弹力管训练或传统阻力训练，为期八周。
主要结局指标为功能运动能力。次要结局指标为外周肌肉力量、通过慢性呼吸系统疾病问卷（CRDQ）评估的健康相关生活质量、去脂体重和细胞因子谱。
八周后，弹力管训练组六分钟内的平均行走距离增加了73米（±69），传统训练组增加了42米（±59）（p<0.05）。两组的肌肉力量和生活质量均有所改善（P<0.05），两组之间无显著差异。两组的去脂体重均有改善趋势（P=0.05）。在第一次和最后一次训练后，两组的白细胞介素1β（IL-1β）和白细胞介素10（IL-10）均升高，而肿瘤坏死因子α（TNF-α）仅在传统训练组中受到刺激。
弹力管训练对功能运动能力的影响大于传统阻力训练。两种干预措施在改善肌肉力量和生活质量方面同样有效。
