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社会心理状况不影响慢性阻塞性肺疾病多学科康复的短期疗效。

Psychosocial conditions do not affect short-term outcome of multidisciplinary rehabilitation in chronic obstructive pulmonary disease.

作者信息

Trappenburg Jacob C, Troosters Thierry, Spruit Martijn A, Vandebrouck Nele, Decramer Marc, Gosselink Rik

机构信息

Respiratory Rehabilitation and Respiratory Division, University Hospitals, Katholieke Universiteit, Leuven, Belgium.

出版信息

Arch Phys Med Rehabil. 2005 Sep;86(9):1788-92. doi: 10.1016/j.apmr.2005.03.030.

Abstract

OBJECTIVES

To characterize patients referred for pulmonary rehabilitation on a large number of psychologic and sociodemographic variables and to determine the contribution of these variables on the response to rehabilitation.

DESIGN

Cross-sectional, explorative.

SETTING

University hospital and outpatient clinic.

PARTICIPANTS

Eighty-one consecutive patients with chronic obstructive pulmonary disease (forced expiratory volume in 1 second, 40%+/-16% of predicted) were included in outpatient pulmonary rehabilitation.

INTERVENTION

Multidisciplinary rehabilitation program.

MAIN OUTCOME MEASURES

Pulmonary function, exercise capacity (Wmax, 6-minute walk test [6MWT]), Chronic Respiratory Disease Questionnaire (CRDQ), Modified Pulmonary Functional Status and Dyspnea Questionnaire (PFSDQ-M), anxiety and depression (Hospital Anxiety and Depression Scale [HADS]) were assessed before and after 3 months rehabilitation. In addition, psychosocial adjustment, social support, marital status, mode of transportation, education, employment, and smoking status were assessed at the start of the rehabilitation.

RESULTS

Rehabilitation improved exercise performance (Wmax, 6+/-12W; P<.01; 6MWT, 41+/-72 m; P<.001), quality of life (CRDQ score, 12+/-13 points; P<.001), functional status (PFSDQ-M activity score, -8+/-11 points; PFSDQ-M dyspnea score, -6+/-12 points; PFSDQ-M fatigue score, -4+/-8 points; all P<.01), HADS anxiety score (-2+/-3 points, P<.01), and HADS depression score (-3+/-3 points, P<.001). In single regression analysis, only baseline depression was weakly negatively correlated with the change in maximal workload. No other relations of initial psychologic or sociodemographic variables with outcome were observed.

CONCLUSIONS

The effects of rehabilitation are not affected by baseline psychosocial factors. Patients with less favorable psychologic or sociodemographic conditions can also benefit from pulmonary rehabilitation. The multidisciplinary approach of the rehabilitation program might have contributed to this improvement.

摘要

目的

根据大量心理和社会人口统计学变量对接受肺康复治疗的患者进行特征描述,并确定这些变量对康复反应的影响。

设计

横断面探索性研究。

地点

大学医院和门诊诊所。

参与者

81例连续的慢性阻塞性肺疾病患者(1秒用力呼气量为预测值的40%±16%)被纳入门诊肺康复治疗。

干预措施

多学科康复计划。

主要观察指标

在康复治疗3个月前后评估肺功能、运动能力(最大摄氧量、6分钟步行试验[6MWT])、慢性呼吸系统疾病问卷(CRDQ)、改良肺功能状态和呼吸困难问卷(PFSDQ-M)、焦虑和抑郁(医院焦虑抑郁量表[HADS])。此外,在康复治疗开始时评估心理社会适应、社会支持、婚姻状况、交通方式、教育程度、就业情况和吸烟状况。

结果

康复治疗改善了运动表现(最大摄氧量,增加6±12W;P<0.01;6MWT,增加41±72m;P<0.001)、生活质量(CRDQ评分,增加12±13分;P<0.001)、功能状态(PFSDQ-M活动评分,降低8±11分;PFSDQ-M呼吸困难评分,降低6±12分;PFSDQ-M疲劳评分,降低4±8分;均P<0.01)、HADS焦虑评分(降低2±3分,P<0.01)和HADS抑郁评分(降低3±3分,P<0.001)。在单因素回归分析中,只有基线抑郁与最大工作量的变化呈弱负相关。未观察到初始心理或社会人口统计学变量与结局之间的其他关系。

结论

康复治疗的效果不受基线心理社会因素的影响。心理或社会人口统计学条件较差的患者也可从肺康复治疗中获益。康复计划的多学科方法可能促成了这种改善。

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