Paletta Guedes Ricardo Augusto, Paletta Guedes Vanessa Maria, Freitas Sirley Maria, Chaoubah Alfredo
Federal University of Juiz de Fora, Juiz de Fora, Brazil ; Paletta Guedes Ophthalmological Center, Juiz de Fora, Brazil ; Santa Casa de Misericórdia Hospital, Juiz de Fora, Brazil.
Paletta Guedes Ophthalmological Center, Juiz de Fora, Brazil.
Clin Ophthalmol. 2014 Mar 12;8:529-35. doi: 10.2147/OPTH.S60105. eCollection 2014.
We sought to identify the utility values in a group of Brazilian patients with primary open-angle glaucoma (POAG), and to assess its impact on visual acuity (VA) and mean deviation index values.
This was a cross-sectional study of consecutive patients with POAG, who were interviewed using three methods for obtaining utility values: time trade-off (TTO), standard gamble anchored at risk of death (SG1), and standard gamble anchored at risk of blindness (SG2). Visual function variables (VA and mean deviation index in the better eye) and sociodemographic characteristics (age, sex, race, and educational level) were also obtained for statistical analysis.
The mean age (± standard deviation) of the study population (n=227) was 65.7 (±15.1) years. Mean utility values for the entire population were 0.82 from TTO, 0.90 from SG1, and 0.93 from SG2 (P<0.0001). Age, race, and sex had no influence on the utility values. Higher education tended to predict higher values by TTO, but not by SG1 or SG2. Visual function variables had an influence on utility values. The more advanced the visual loss, whether measured by VA or perimetry, in the better eye, the lower the utility values by all three methods.
We obtained utility values for Brazilian patients with POAG, as well as specific values for different levels of vision loss.
我们试图确定一组巴西原发性开角型青光眼(POAG)患者的效用值,并评估其对视力(VA)和平均偏差指数值的影响。
这是一项对连续性POAG患者的横断面研究,采用三种获取效用值的方法对患者进行访谈:时间权衡法(TTO)、以死亡风险为锚定的标准博弈法(SG1)和以失明风险为锚定的标准博弈法(SG2)。还获取了视觉功能变量(较好眼的VA和平均偏差指数)和社会人口学特征(年龄、性别、种族和教育水平)用于统计分析。
研究人群(n = 227)的平均年龄(±标准差)为65.7(±15.1)岁。整个人群的平均效用值TTO法为0.82,SG1法为0.90,SG2法为0.93(P<0.0001)。年龄、种族和性别对效用值无影响。高等教育倾向于预测TTO法得出的较高值,但SG1法或SG2法并非如此。视觉功能变量对效用值有影响。较好眼中,无论通过VA还是视野测量,视觉损失越严重,三种方法得出的效用值越低。
我们得出了巴西POAG患者的效用值,以及不同视力丧失水平的具体值。