Quigley H A, Broman A T
The Glaucoma Service and the Dana Center for Preventive Opthalmalogy, Wilmer Opthalmological Institute, Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287, USA.
Br J Ophthalmol. 2006 Mar;90(3):262-7. doi: 10.1136/bjo.2005.081224.
To estimate the number of people with open angle (OAG) and angle closure glaucoma (ACG) in 2010 and 2020.
A review of published data with use of prevalence models. Data from population based studies of age specific prevalence of OAG and ACG that satisfied standard definitions were used to construct prevalence models for OAG and ACG by age, sex, and ethnicity, weighting data proportional to sample size of each study. Models were combined with UN world population projections for 2010 and 2020 to derive the estimated number with glaucoma.
There will be 60.5 million people with OAG and ACG in 2010, increasing to 79.6 million by 2020, and of these, 74% will have OAG. Women will comprise 55% of OAG, 70% of ACG, and 59% of all glaucoma in 2010. Asians will represent 47% of those with glaucoma and 87% of those with ACG. Bilateral blindness will be present in 4.5 million people with OAG and 3.9 million people with ACG in 2010, rising to 5.9 and 5.3 million people in 2020, respectively.
Glaucoma is the second leading cause of blindness worldwide, disproportionately affecting women and Asians.
估算2010年和2020年开角型青光眼（OAG）和闭角型青光眼（ACG）患者的人数。
利用患病率模型对已发表的数据进行综述。来自符合标准定义的基于人群的OAG和ACG年龄特异性患病率研究的数据，用于构建按年龄、性别和种族划分的OAG和ACG患病率模型，根据每项研究的样本量对数据进行加权。将模型与联合国2010年和2020年世界人口预测相结合，得出青光眼患者的估计人数。
2010年将有6050万人患有OAG和ACG，到2020年将增至7960万人，其中74%将患有OAG。2010年，女性将占OAG患者的55%、ACG患者的70%以及所有青光眼患者的59%。亚洲人将占青光眼患者的47%和ACG患者的87%。2010年，450万OAG患者和390万ACG患者将出现双侧失明，到2020年将分别增至590万和530万人。
青光眼是全球第二大致盲原因，对女性和亚洲人的影响尤为严重。
