de Araújo Arão Nogueira, do Nascimento Marion Alves, de Sena Eduardo Pondé, Baptista Abrahão Fontes
Postgraduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia, Salvador, Brazil.
Postgraduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia, Salvador, Brazil ; Department of Pharmacology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Drug Healthc Patient Saf. 2014 Mar 10;6:21-7. doi: 10.2147/DHPS.S57172. eCollection 2014.
Patients with psychiatric problems show a tendency to develop temporomandibular disorders (TMD). Particularly, patients with schizophrenia are quite likely to have signs and symptoms of TMD due to the impairment of their oral health, the use of antipsychotic drugs, and other general health problems. In nonschizophrenic populations, TMD have been considered as the main cause of nondental pain in the orofacial region, involving mechanisms associated with changes in masticatory activity at the cortical and neuromuscular levels. Individuals with schizophrenia do not usually complain of pain, and TMD is misdiagnosed in this population. In this paper, we aimed to review the clinical aspects of TMD in people with schizophrenia on antipsychotic drug therapy.
患有精神疾病的患者有患颞下颌关节紊乱症（TMD）的倾向。特别是，精神分裂症患者很可能由于口腔健康受损、使用抗精神病药物以及其他一般健康问题而出现TMD的体征和症状。在非精神分裂症人群中，TMD被认为是口面部区域非牙源性疼痛的主要原因，涉及与皮质和神经肌肉水平咀嚼活动变化相关的机制。精神分裂症患者通常不会主诉疼痛，因此该人群中的TMD常被误诊。在本文中，我们旨在综述接受抗精神病药物治疗的精神分裂症患者TMD的临床情况。
